Evidence map›Paper›PMID 29644238›Full record

ReviewMedical hypothesis, discovery & innovation ophthalmology journal2018

Mechanisms of Optical Regression Following Corneal Laser Refractive Surgery: Epithelial and Stromal Responses.

Majid Moshirfar, Jordan D Desautels, Brian D Walker, Michael S Murri, Orry C Birdsong, Phillip C Sr Hoopes

Abstract readReview
In one paragraph

Review in Medical hypothesis, discovery & innovation ophthalmology journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Trial
  2. Article
  3. Changes in corneal epithelial remodeling and associated factors in highly myopic patients after FS-LASIK.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
  4. Article
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  6. Late onset bilateral annular subepithelial corneal haze after LASIK.American journal of ophthalmology case reports · 2025
    Article
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  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Majid MoshirfarJohn A. Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah School of Medicine, 50 North Medical Dr., Salt Lake City, UT 84132, United States.
Jordan D DesautelsHDR Research Center, Hoopes Vision, 11820 S. State Street Suite #200, Draper, UT 84020, United States.
Brian D WalkerMcGovern Medical School, The University of Texas Health Science Center at Houston, 6431 Fannin St, Houston, TX 77030, United States.
Michael S MurriJohn A. Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah School of Medicine, 50 North Medical Dr., Salt Lake City, UT 84132, United States.
Orry C BirdsongHDR Research Center, Hoopes Vision, 11820 S. State Street Suite #200, Draper, UT 84020, United States.
Phillip C Sr HoopesHDR Research Center, Hoopes Vision, 11820 S. State Street Suite #200, Draper, UT 84020, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Laser vision correction is a safe and effective method of reducing spectacle dependence. Photorefractive Keratectomy (PRK), Laser In Situ Keratomileusis (LASIK), and Small-Incision Lenticule Extraction (SMILE) can accurately correct myopia, hyperopia, and astigmatism. Although these procedures are nearing optimization in terms of their ability to produce a desired refractive target, the long term cellular responses of the cornea to these procedures can cause patients to regress from the their ideal postoperative refraction. In many cases, refractive regression requires follow up enhancement surgeries, presenting additional risks to patients. Although some risk factors underlying refractive regression have been identified, the exact mechanisms have not been elucidated. It is clear that cellular proliferation events are important mediators of optical regression. This review focused specifically on cellular changes to the corneal epithelium and stroma, which may influence postoperative visual regression following LASIK, PRK, and SMILE procedures.

Indexed as

AstigmatismCornealEpitheliumHyperopiaKeratomileusisLaser In SituMyopiaPhotorefractive KeratectomyRefractive Surgical Procedures

Identifiers

PMID29644238
PMCPMC5887600

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.