Evidence map›Paper›PMID 29644192›Full record

ArticleIndian dermatology online journal

Is Antifungal Resistance a Cause for Treatment Failure in Dermatophytosis: A Study Focused on Tinea Corporis and Cruris from a Tertiary Centre?

Kabir Sardana, Ravinder Kaur, Pooja Arora, Ritu Goyal, Sneha Ghunawat

Open access · diamondAbstract read
In one paragraph

Article in Indian dermatology online journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.

  1. Pooled it
  2. Journal of clinical microbiology · 2026
    Article
  3. Emerging Global Patterns of Terbinafine Resistance inAntibiotics (Basel, Switzerland) · 2026
    Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Antifungal Combinations in Dermatophytes.Journal of fungi (Basel, Switzerland) · 2021
    Review
  13. Molecular Epidemiology and Antifungal Susceptibility ofJournal of fungi (Basel, Switzerland) · 2021
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Kabir SardanaDepartment of Dermatology, Dr. Ram Manohar Lohia Hospital and PGIMER, New Delhi, India.
Ravinder KaurDepartment of Microbiology, Lady Hardinge Medical College, New Delhi, India.
Pooja AroraDepartment of Dermatology, Dr. Ram Manohar Lohia Hospital and PGIMER, New Delhi, India.
Ritu GoyalDepartment of Microbiology, Maulana Azad Medical College, New Delhi, India.
Sneha GhunawatDepartment of Dermatology, Maulana Azad Medical College, New Delhi, India.
Lady Hardinge Medical College · INMaulana Azad Medical College · INAtal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDermatophytoses are one of the most common skin diseases that have been largely simple to treat. However, in recent years, these infections have become recalcitrant to treatment which can possibly be due to antifungal resistance.

aimTo analyze the resistance pattern of patients with recalcitrant dermatophytoses. MATERIALS AND

methodsA cross-sectional evaluation was undertaken of 40 consecutive patients with recalcitrant tinea corporis/cruris/both who had taken systemic antifungal treatment and did not respond completely to therapy or had recurrent lesion within 1 month of stopping the therapy. Terbinafine, fluconazole, itraconazole, ketoconazole, amphotericin B, and voriconazole were the antifungals tested using broth microdilution assay for antifungal susceptibility testing of dermatophytes, and MIC50, 90 values were recorded.

resultsKOH mount was positive in 18 (45%) patients, culture was positive in 28 (70%) patients.

conclusionWhile MIC seen were higher than western data,

Indexed as

AntifungalsdermatophytosisitraconazoleMICresistanceterbinafinetinea

Identifiers

PMID29644192
PMCPMC5885633
OpenAlexW2791939553

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.