ArticleRegenerative biomaterials2018
Anti-biofilm and remineralization effects of chitosan hydrogel containing amelogenin-derived peptide on initial caries lesions.
Article in Regenerative biomaterials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Peptide Designs for Use in Caries Management: A Systematic Review.International journal of molecular sciences · 2023Pooled it
- Optimization of In Vitro White Spot Lesion Protocol: Comparative Diagnostics via Visual Inspection, Scanning Electron Microscopy, and Fluorescence Methods.Diagnostics (Basel, Switzerland) · 2026Article
- Application of Polymers in Advanced Materials for Enamel and Dentine Remineralization.ACS biomaterials science & engineering · 2026Review
- Advanced biomimetic mineralization approaches for enamel and dentin regeneration: a review.Odontology · 2026Review
- Comparison of the Caries Remineralizing Effects of Dentifrices Based on Natural Hydroxyapatite, Synthetic Hydroxyapatite, and Fluoride: A pH Cycling Study.Biomimetics (Basel, Switzerland) · 2026Article
- The advancement of nanosystems for drug delivery in the prevention and treatment of dental caries.Frontiers in cellular and infection microbiology · 2025Review
- Developing functional hydrogels for treatment of oral diseases.Smart medicine · 2024Review
- Thermosensitive hydrogel with programmed dual-octenidine release combating biofilm for the treatment of apical periodontitis.Regenerative biomaterials · 2024Article
- Peptides in Dentistry: A Scoping Review.Bioengineering (Basel, Switzerland) · 2023Article
- Chitosan as a biomaterial for the prevention and treatment of dental caries: antibacterial effect, biomimetic mineralization, and drug delivery.Frontiers in bioengineering and biotechnology · 2023Review
- Advanced materials for enamel remineralization.Frontiers in bioengineering and biotechnology · 2022Review
- Advances in biomineralization-inspired materials for hard tissue repair.International journal of oral science · 2021Review
- Advanced non-fluoride approaches to dental enamel remineralization: The next level in enamel repair management.Biomaterials and biosystems · 2021Review
- Comparison of the effect of fluoride gel and two toothpastes with different materials on remineralization of initial carious lesions in primary teeth.Journal of family medicine and primary care · 2021Article
- Remineralization of enamel caries by an amelogenin-derived peptide and fluorideRegenerative biomaterials · 2020Article
- Role of Chitosan in Remineralization of Enamel and Dentin: A Systematic Review.International journal of clinical pediatric dentistryReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this study, we have designed a more clinically powerful anti-caries treatment by applying the amelogenin-derived peptide QP5 to the antibacterial carrier material chitosan in a hydrogel (CS-QP5 hydrogel), and characterized its effects on the inhibition of a cariogenic biofilm and the promotion of the remineralization of the initial caries lesions. The results indicated that the CS-QP5 hydrogel sustainably inhibited the growth of the
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.