ArticleJournal of animal science and biotechnology2018
Regulation of amino acid transporters in the mammary gland from late pregnancy to peak lactation in the sow.
Article in Journal of animal science and biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 26 citations in OpenAlex.
- Integrating omics and functional data via representation learning to prioritize candidate genes for pleiotropic effect in dairy sheep.PNAS nexus · 2025Article
- The Influence of Genotype and Seasonality on the Sow Colostrum Quality and Immunoglobulin G Content.Animals : an open access journal from MDPI · 2025Article
- Nettle supplementation improves antioxidant status and modulates inflammatory response by altering lysophosphatidylcholines and enterolactone metabolism in dairy cows.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2025Article
- Adipose gene expression profiles in Northern Finncattle, Mirandesa cattle, Yakutian cattle and commercial Holstein cattle.Scientific reports · 2024Article
- The Selenium Yeast vs Selenium Methionine on Cell Viability, Selenoprotein Profile and Redox StatusFrontiers in veterinary science · 2022Article
- A review of branched-chain amino acids in lactation diets on sow and litter growth performance.Translational animal science · 2022Article
- Dietary fiber in a low-protein diet during gestation affects nitrogen excretion in primiparous gilts, with possible influences from the gut microbiota.Journal of animal science · 2021Article
- Article
- Recent progress of porcine milk components and mammary gland function.Journal of animal science and biotechnology · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMilk protein is crucial for milk quality in sows and health of newborn piglets. Plasma amino acids (AA) in sows are important precursors for milk protein synthesis in the mammary gland. In order to study the regulation of AA transported in sow mammary glands and possible underlying mechanisms, we measured the expression of genes coding for milk proteins, AA transporter expressions, and plasma AA concentrations in sows at three different physiological stages (D-17, D1 and D17 of lactation), and then further investigated the regulation of AA transport across the cell membrane by adaptive mechanisms using pig mammary epithelial cells (PMEC) as an in vitro model. PMEC were cultured in DMEM:F12 with 4 amino acid concentrations (0 × AA complex, 1 × AA complex, 5 × AA complex, and 25 × AA complex). Classes of AA complexes evaluated in this study included neutral AAs (
resultsOur results indicated that mRNA expression of genes coding for milk protein (αs1-casein, αs2-casein, β-casein and κ-casein) increased significantly with the advance of physiological stage (
conclusionAA transportation was positively regulated in sow mammary glands with the advance of physiological stage from late pregnancy to peak of lactation and AA transporters in PMECs were adaptively regulated by changed AA concentrations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.