Evidence map›Paper›PMID 29644007›Full record

ArticleOncotarget2018

Impact of adjuvant hormonotherapy on radiation-induced breast fibrosis according to the individual radiosensitivity: results of a multicenter prospective French trial.

Céline Bourgier, Florence Castan, Olivier Riou, Tan-Dat Nguyen, Karine Peignaux, Claire Lemanski, Jean-Léon Lagrange, Youlia Kirova, Eric Lartigau, Yazid Belkacemi and 10 more

2 registry-linked trialsOpen access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00893035 completednot on this map

Multicenter Prospective Evaluation of a Predictive Test of Late Toxicities After Radiotherapy by the Rate of Radiation Induced CD8 T-Lymphocyte Apoptosis: Application to Breast and Prostate Cancers.

TypeobservationalSponsorInstitut du Cancer de Montpellier - Val d'AurelleRan2006 to 2019Enrolled885ConditionsBreast Cancer, Prostate Cancer
NCT04282122 recruitingnot on this mapstarted 2019, after this paper: background citation

Establishment of a Prospective Evaluation of Daily Practice Including the Individual Radiosensitivity Test to the Decision of Daily Practice

TypeobservationalSponsorInstitut du Cancer de Montpellier - Val d'AurelleRan2019 to 2026Enrolled500ConditionsBreast CancerArmsRadiotherapy
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
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  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 12 institutions in 2 countries.

Céline BourgierInstitute de Recherche en Cancérologie de Montpellier, Inserm U1194, Université de Montpellier, Institut Régional du Cancer de Montpellier, Montpellier, France.
Florence CastanInstitute de Recherche en Cancérologie de Montpellier, Inserm U1194, Université de Montpellier, Institut Régional du Cancer de Montpellier, Montpellier, France.
Olivier RiouInstitute de Recherche en Cancérologie de Montpellier, Inserm U1194, Université de Montpellier, Institut Régional du Cancer de Montpellier, Montpellier, France.
Tan-Dat NguyenInstitute Jean Godinot, Reims, France.
Karine PeignauxCentre GF Leclerc, Dijon, France.
Claire LemanskiInstitute de Recherche en Cancérologie de Montpellier, Inserm U1194, Université de Montpellier, Institut Régional du Cancer de Montpellier, Montpellier, France.
Jean-Léon LagrangeAP-HP Henri Mondor, Créteil, France.
Youlia KirovaInstitute Curie, Paris, France.
Eric LartigauCentre Oscar Lambret, Lille, France.
Yazid BelkacemiAP-HP Henri Mondor, Créteil, France.
Sofia RiveraGustave Roussy, Villejuif, France.
Georges NoëlCentre Paul Strauss, Strasbourg, France.
Sébastien ClippeCentre Marie Curie, Valence, France.
Françoise MornexCentre Hospitalier Lyon Sud, Pierre Bénite, France.
Christophe HennequinAP-HP Saint-Louis, Paris, France.
Sophie GourgouInstitute de Recherche en Cancérologie de Montpellier, Inserm U1194, Université de Montpellier, Institut Régional du Cancer de Montpellier, Montpellier, France.
Muriel BrenguesInstitute de Recherche en Cancérologie de Montpellier, Inserm U1194, Université de Montpellier, Institut Régional du Cancer de Montpellier, Montpellier, France.
Pascal FenogliettoInstitute de Recherche en Cancérologie de Montpellier, Inserm U1194, Université de Montpellier, Institut Régional du Cancer de Montpellier, Montpellier, France.
Esat Mahmut OzsahinCentre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
David AzriaInstitute de Recherche en Cancérologie de Montpellier, Inserm U1194, Université de Montpellier, Institut Régional du Cancer de Montpellier, Montpellier, France.
Assistance Publique – Hôpitaux de Paris · FRInserm · FRInstitut Regional du Cancer de MontpellierUniversité de Montpellier · FRCentre Georges François Leclerc · FRCentre Hospitalier de Valence · FRCentre Oscar Lambret · FRHôpital Lyon Sud · FRInstitut Curie · FRInstitut Gustave Roussy · FRInstitut Jean Godinot · FRUniversity Hospital of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo evaluate risk of severe breast fibrosis occurrence in patients treated by breast-conserving surgery, adjuvant radiotherapy and hormonotherapy (HT) according to individual radiosensitivity (RILA assay).

resultsHT

conclusionsHT and RILA score independently influenced BFFS rate at 36 months. Patients with RILA MATERIALS AND

methodsBreast Fibrosis-Free Survival (BFFS) rate was assessed relative to RILA categories and to adjuvant HT use (HT

Indexed as

breast cancerhormonotherapyindividual radiosensitivitylate effectsradiotherapy

Identifiers

PMID29644007
PMCPMC5884662
OpenAlexW2789664250

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.