Evidence map›Paper›PMID 29644005›Full record

ArticleOncotarget2018

Radiofrequency assisted pancreaticoduodenectomy for palliative surgical resection of locally advanced pancreatic adenocarcinoma.

Jayant Kumar, Isabella Reccia, Mikael H Sodergren, Tomokazu Kusano, Artur Zanellato, Madhava Pai, Duncan Spalding, Dimitris Zacharoulis, Nagy Habib

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Jayant KumarDepartment of Surgery and Cancer, Hammersmith Campus, Imperial College London, London, UK.
Isabella RecciaDepartment of Surgery and Cancer, Hammersmith Campus, Imperial College London, London, UK.
Mikael H SodergrenDepartment of Surgery and Cancer, Hammersmith Campus, Imperial College London, London, UK.
Tomokazu KusanoDepartment of Surgery and Cancer, Hammersmith Campus, Imperial College London, London, UK.
Artur ZanellatoDepartment of Surgery and Cancer, Hammersmith Campus, Imperial College London, London, UK.
Madhava PaiDepartment of Surgery and Cancer, Hammersmith Campus, Imperial College London, London, UK.
Duncan SpaldingDepartment of Surgery and Cancer, Hammersmith Campus, Imperial College London, London, UK.
Dimitris ZacharoulisDepartment of General Surgery, University Hospital of Larissa, Larissa, Greece.
Nagy HabibDepartment of Surgery and Cancer, Hammersmith Campus, Imperial College London, London, UK.
Hammersmith Hospital · GBImperial College London · GBUniversity Hospital of Larissa · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite careful patient selection and preoperative investigations curative resection rate (R0) in pancreaticoduodenectomy ranges from 15% to 87%. Here we describe a new palliative approach for pancreaticoduodenectomy using a radiofrequency energy device to ablate tumor

resultsThere was neither postoperative mortality nor significant morbidity. Each time the ablation lasted less than 15 minutes. Following radiofrequency ablation it was observed that the tumor remnant attached to the vessel had shrunk significantly. In four patients this allowed easier separation and dissection of the ablated tumor from the adherent vessel leading to R1 resection. In the other two patients, the ablated tumor did not separate from vessel due to true tumor invasion and patients had an R2 resection. The ablated remnant part of the tumor was left

conclusionWhenever pancreaticoduodenectomy with R0 resection cannot be achieved, this new palliative procedure could be considered in order to facilitate resection and enable maximum destruction in remnant tumors.

methodSix patients with suspected tumor infiltration and where vascular reconstruction was not warranted underwent radiofrequency-assisted pancreaticoduodenectomy for locally advanced pancreatic ductal adenocarcinoma. Radiofrequency was applied across the tumor vertically 5-10 mm from the edge of the mesenteric and portal veins. Following ablation, the duodenum and the head of pancreas were removed after knife excision along the ablated line. The remaining ablated tissue was left

Indexed as

palliationpancreatic ductal adenocarcinomapancreaticoduodenectomyradiofrequency ablation

Identifiers

PMID29644005
PMCPMC5884660
OpenAlexW2792836112

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.