Evidence map›Paper›PMID 29643996›Full record

ArticleOncotarget2018

Selective lysis of breast carcinomas by simultaneous stimulation of sodium channels and blockade of sodium pumps.

Harry J Gould, Jack Norleans, T David Ward, Chasiti Reid, Dennis Paul

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

  1. Pharmaceuticals (Basel, Switzerland) · 2026
    Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Targeting Ion Channels for Cancer Treatment: Current Progress and Future Challenges.Reviews of physiology, biochemistry and pharmacology · 2022
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Sodium homeostasis in the tumour microenvironment.Biochimica et biophysica acta. Reviews on cancer · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Harry J GouldDepartment of Neurology, Louisiana State University Health Sciences Center, New Orleans, LA, USA.
Jack NorleansDepartment of Pharmacology and Experimental Therapeutics, Louisiana State University Health Sciences Center, New Orleans, LA, USA.
T David WardDepartment of Cell Biology and Anatomy, Louisiana State University Health Sciences Center, New Orleans, LA, USA.
Chasiti ReidDepartment of Pharmacology and Experimental Therapeutics, Louisiana State University Health Sciences Center, New Orleans, LA, USA.
Dennis PaulDepartment of Neurology, Louisiana State University Health Sciences Center, New Orleans, LA, USA.
Louisiana State University Health Sciences Center New Orleans · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sodium influx through voltage-gated sodium channels (VGSCs) coupled with balanced removal of sodium ions via Na

Indexed as

cancerepithelial carcinomasodium channelssodium pumpstargeted osmotic lysis

Identifiers

PMID29643996
PMCPMC5884651
OpenAlexW2790549802

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.