ArticleBioPsychoSocial medicine2018
Changes in fatigue, autonomic functions, and blood biomarkers due to sitting isometric yoga in patients with chronic fatigue syndrome.
Article in BioPsychoSocial medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 5 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 5 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Optimized exercise prescription for alleviating cancer-related fatigue in breast cancer survivors after primary treatment: a systematic review and dose-response network meta-analysis.Frontiers in public health · 2026Pooled it
- Recent research in myalgic encephalomyelitis/chronic fatigue syndrome: an evidence map.Health technology assessment (Winchester, England) · 2025Pooled it
- Systematic Review of Mind-Body Interventions to Treat Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.Medicina (Kaunas, Lithuania) · 2021Pooled it
- The evidence base for physiotherapy in myalgic encephalomyelitis/chronic fatigue syndrome when considering post-exertional malaise: a systematic review and narrative synthesis.Journal of translational medicine · 2021Pooled it
- Associations Between Psychological and Immunological Variables in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis: A Systematic Review.Frontiers in psychiatry · 2021Pooled it
- Assessing changes in mood state in university students following short-term study abroad.PloS one · 2021Trial
- Effects of recumbent isometric yoga on the daily functioning level of patients with myalgic encephalomyelitis/chronic fatigue syndrome: a randomized, controlled trial.BioPsychoSocial medicine · 2025Article
- Effects of recumbent isometric yoga on the orthostatic cardiovascular response of patients with myalgic encephalomyelitis/chronic fatigue syndrome.BioPsychoSocial medicine · 2025Article
- Yoga as a Fatigue Intervention for Children Who Are Deaf and Hard of Hearing.Perspectives of the ASHA special interest groups · 2025Article
- Article
- Perceived benefit of yoga among adults who have practiced yoga for a long time: a qualitative study.BioPsychoSocial medicine · 2023Article
- Yoga for COVID-19: An ancient practice for a new condition - A literature review.Complementary therapies in clinical practice · 2023Review
- Effect of intensive weekend mindfulness-based intervention on BDNF, mitochondria function, and anxiety. A randomized, crossover clinical trial.Comprehensive psychoneuroendocrinology · 2022Article
- The development and clinical application of a novel schizophrenia screening system using yoga-induced autonomic nervous system responses.Frontiers in physiology · 2022Article
- Health-related benefits and adverse events associated with yoga classes among participants that are healthy, in poor health, or with chronic diseases.BioPsychoSocial medicine · 2021Article
- CLARIFY 2021: explanation and elaboration of the Delphi-based guidelines for the reporting of yoga research.BMJ open · 2021Article
- Increase in rear-end collision risk by acute stress-induced fatigue in on-road truck driving.PloS one · 2021Article
- Effects of meditation and mind-body exercise on brain-derived neurotrophic factor: A literature review of human experimental studies.Sports medicine and health science · 2020Review
- Reduced heart rate variability predicts fatigue severity in individuals with chronic fatigue syndrome/myalgic encephalomyelitis.Journal of translational medicine · 2020Article
- Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn a previous randomized controlled trial, we found that sitting isometric yoga improves fatigue in patients with chronic fatigue syndrome (CFS) who are resistant to conventional therapy. The aim of this study was to investigate possible mechanisms behind this finding, focusing on the short-term fatigue-relieving effect, by comparing autonomic nervous function and blood biomarkers before and after a session of isometric yoga.
methodsFifteen patients with CFS who remained symptomatic despite at least 6 months of conventional therapy practiced sitting isometric yoga (biweekly 20 min practice with a yoga instructor and daily home practice) for eight weeks. Acute effects of sitting isometric yoga on fatigue, autonomic function, and blood biomarkers were investigated after the final session with an instructor. The effect of a single session of sitting isometric yoga on fatigue was assessed by the Profile of Mood Status (POMS) questionnaire immediately before and after the session. Autonomic nervous function (heart rate (HR) variability) and blood biomarkers (cortisol, DHEA-S, TNF-α, IL-6, IFN-γ, IFN-α, prolactin, carnitine, TGF-β1, BDNF, MHPG, and HVA) were compared before and after the session.
resultsSitting isometric yoga significantly reduced the POMS fatigue score (
conclusionsA single session of sitting isometric yoga reduced fatigue and increased vigor in patients with CFS. Yoga also increased vagal nerve function and changed blood biomarkers in a pattern that suggested anti-stress and anti-inflammatory effects. These changes appear to be related to the short-term fatigue-relieving effect of sitting isometric yoga in patients with CFS. Furthermore, dopaminergic nervous system activation might account for sitting isometric yoga-induced increases in energy in this patient population.
trial registrationUniversity Hospital Medical Information Network (UMIN CTR) UMIN000009646. Registered Dec 27, 2012.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.