Evidence map›Paper›PMID 29643908›Full record

ArticlePakistan journal of medical sciences

Lack of association of statin use with vitamin D levels in a hospital based population of type 2 diabetes mellitus patients.

Khalida Iqbal, Najmul Islam, Iqbal Azam, Naseema Mehboobali, Mohammad Perwaiz Iqbal

Abstract read
In one paragraph

Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Khalida IqbalKhalida Iqbal, Department of Biological & Biomedical Sciences, Aga Khan University, Karachi, Pakistan.
Najmul IslamNajmul Islam, Department of Medicine, Aga Khan University, Karachi, Pakistan.
Iqbal AzamIqbal Azam, Department of Community Health Sciences, Aga Khan University, Karachi, Pakistan.
Naseema MehboobaliNaseema Mehboobali, Department of Biological & Biomedical Sciences, Aga Khan University, Karachi, Pakistan.
Mohammad Perwaiz IqbalMohammad Perwaiz Iqbal, Department of Biological & Biomedical Sciences, Aga Khan University, Karachi, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the relationship of statins (drug given to reduce serum levels of LDL-cholesterol) on vitamin D levels of Pakistani type 2 diabetes mellitus (DM) patients in a hospital in Karachi.

methodsIn a cross-sectional survey, 312 consecutive patients with type 2 DM (219 males and 93 females, age 22-70 years) were recruited with informed consent. A questionnaire was administered to find out whether they were statin users or non-users. Serum was analyzed for concentrations of 25(OH) vitamin D [25(OH)D] and other related biomarkers such as serum cholesterol, triglycerides, HDL-cholesterol, LDL-cholesterol, phosphate and calcium using kit methods. Multiple Linear Regression was used to evaluate association of statin use with serum levels of vitamin D while adjusting for related covariates including duration of statin use, duration of type 2 DM and smoking.

resultsMean concentrations of serum cholesterol, and LDL-cholesterol were lower among statin users compared to statin non-users (

conclusionLack of association was found between statin use and vitamin D levels in a hospital-based population of Pakistani patients with type 2 DM.

Indexed as

Diabetes mellitusPakistani populationStatinsVitamin D levels

Identifiers

PMID29643908
PMCPMC5857014

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.