ReviewFrontiers in endocrinology2018
Metabolic Impact on the Hypothalamic Kisspeptin-Kiss1r Signaling Pathway.
Review in Frontiers in endocrinology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 42 citations in OpenAlex.
- Article
- Article
- Chronobiotic and cytoprotective activity of melatonin in the cardiovascular system. Doses matter.Npj biological timing and sleep · 2024Review
- Sertoli cell-conditioned medium can improve blood-testis-barrier function and spermatogenesis in azoospermia mice induced by scrotal hyperthermia: An experimental study.International journal of reproductive biomedicine · 2024Article
- Melatonin as a Chronobiotic and Cytoprotector in Non-communicable Diseases: More than an Antioxidant.Sub-cellular biochemistry · 2024Review
- Metabolomic disorders caused by an imbalance in the gut microbiota are associated with central precocious puberty.Frontiers in endocrinology · 2024Article
- Food deprivation differentially modulates gene expression of LPXRFa and kisspeptin systems in the brain-pituitary axis of half-smooth tongue sole (Frontiers in endocrinology · 2023Article
- Performance of Marmoset Monkeys as Embryo Donors Is Reflected by Different Stress-Related Parameters.Animals : an open access journal from MDPI · 2022Article
- Sexual Dimorphism in Kisspeptin Signaling.Cells · 2022Review
- Effects of low energy availability on female reproductive function.Reproductive medicine and biology · 2022Review
- RF-amide related peptide-3 (RFRP-3): a novel neuroendocrine regulator of energy homeostasis, metabolism, and reproduction.Molecular biology reports · 2021Review
- High-Throughput Screening of Mouse Gene Knockouts Identifies Established and Novel High Body Fat Phenotypes.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021Article
- Peripheral action of kisspeptin at reproductive tissues-role in ovarian function and embryo implantation and relevance to assisted reproductive technology in livestock: a review.Biology of reproduction · 2020Review
- A selective serotonin receptor agonist for weight loss and management of menopausal vasomotor symptoms in overweight midlife women: a pilot study.Menopause (New York, N.Y.) · 2020Article
- Targeted Deletion of PTEN in Kisspeptin Cells Results in Brain Region- and Sex-Specific Effects on Kisspeptin Expression and Gonadotropin Release.International journal of molecular sciences · 2020Article
- Functional hypothalamic and drug-induced amenorrhea: an overview.Journal of endocrinological investigation · 2019Review
- Effects of Low Energy Availability on Reproductive Functions and Their Underlying Neuroendocrine Mechanisms.Journal of clinical medicine · 2018Review
- Lipid Metabolism Alteration by Endocrine Disruptors in Animal Models: An Overview.Frontiers in endocrinology · 2018Review
- Article
- Autoimmune Thyroid Disease and Female Fertility: Clinical Evidence on Ovarian Reserve, Infertility Treatment Outcomes, and Pathophysiology.Reproductive medicine and biologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A large body of data has established the hypothalamic kisspeptin (KP) and its receptor, KISS1R, as major players in the activation of the neuroendocrine reproductive axis at the time of puberty and maintenance of reproductive capacity in the adult. Due to its strategic location, this ligand-receptor pair acts as an integrator of cues from gonadal steroids as well as of circadian and seasonal variation-related information on the reproductive axis. Besides these cues, the activity of the hypothalamic KP signaling is very sensitive to the current metabolic status of the body. In conditions of energy imbalance, either positive or negative, a number of alterations in the hypothalamic KP signaling pathway have been documented in different mammalian models including nonhuman primates and human. Deficiency of metabolic fuels during fasting causes a marked reduction of
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.