Evidence map›Paper›PMID 29643817›Full record

ArticleFrontiers in physiology2018

Overexpression of ß-Arrestin1 in the Rostral Ventrolateral Medulla Downregulates Angiotensin Receptor and Lowers Blood Pressure in Hypertension.

Jia-Cen Sun, Bing Liu, Ru-Wen Zhang, Pei-Lei Jiao, Xing Tan, Yang-Kai Wang, Wei-Zhong Wang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

  1. The sympathetic nervous system in the pathophysiology of hypertension: Mechanistic insights and therapeutic implications.Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Review
  2. Single-nucleus RNA sequencing reveals Cntnap2Journal of advanced research · 2026
    Article
  3. Article
  4. Article
  5. Insights Into the Role of Angiotensin-II ATHypertension (Dallas, Tex. : 1979) · 2024
    Review
  6. Article
  7. β-Arrestin-Biased Agonist Targeting the Brain ATHypertension (Dallas, Tex. : 1979) · 2021
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jia-Cen SunDepartment of Physiology and Center of Polar Medical Research, Second Military Medical University, Shanghai, China.
Bing LiuDepartment of Physiology and Center of Polar Medical Research, Second Military Medical University, Shanghai, China.
Ru-Wen ZhangDepartment of Physiology and Center of Polar Medical Research, Second Military Medical University, Shanghai, China.
Pei-Lei JiaoDepartment of Physiology and Center of Polar Medical Research, Second Military Medical University, Shanghai, China.
Xing TanDepartment of Physiology and Center of Polar Medical Research, Second Military Medical University, Shanghai, China.
Yang-Kai WangDepartment of Physiology and Center of Polar Medical Research, Second Military Medical University, Shanghai, China.
Wei-Zhong WangDepartment of Physiology and Center of Polar Medical Research, Second Military Medical University, Shanghai, China.
Second Military Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AT1RhypertensionNFκBRVLMsympathetic activityβ-arrestin1

Identifiers

PMID29643817
PMCPMC5882868
OpenAlexW2795268298

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.