Evidence map›Paper›PMID 29643812›Full record

ArticleFrontiers in physiology2018

Left Ventricular Wall Stress Is Sensitive Marker of Hypertrophic Cardiomyopathy With Preserved Ejection Fraction.

Xiaodan Zhao, Ru-San Tan, Hak-Chiaw Tang, Soo-Kng Teo, Yi Su, Min Wan, Shuang Leng, Jun-Mei Zhang, John Allen, Ghassan S Kassab and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Xiaodan ZhaoNational Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, Singapore.
Ru-San TanNational Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, Singapore.
Hak-Chiaw TangNational Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, Singapore.
Soo-Kng TeoInstitute of High Performance Computing, Agency for Science, Technology and Research, Singapore, Singapore.
Yi SuInstitute of High Performance Computing, Agency for Science, Technology and Research, Singapore, Singapore.
Min WanSchool of Information Engineering, Nanchang University, Nanchang, Jiangxi, China.
Shuang LengNational Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, Singapore.
Jun-Mei ZhangNational Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, Singapore.
John AllenDuke-NUS Medical School, Singapore, Singapore.
Ghassan S KassabCalifornia Medical Innovations Institute, San Diego, CA, United States.
Liang ZhongNational Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, Singapore.
Duke-NUS Medical School · SGAgency for Science, Technology and Research · SGNational Heart Centre Singapore · SGCalifornia Medical Innovations Institute · USNanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertrophic cardiomyopathy (HCM) patients present altered myocardial mechanics due to the hypertrophied ventricular wall and are typically diagnosed by the increase in myocardium wall thickness. This study aimed to quantify regional left ventricular (LV) shape, wall stress and deformation from cardiac magnetic resonance (MR) images in HCM patients and controls, in order to establish superior measures to differentiate HCM from controls. A total of 19 HCM patients and 19 controls underwent cardiac MR scans. The acquired MR images were used to reconstruct 3D LV geometrical models and compute the regional parameters (i.e., wall thickness, curvedness, wall stress, area strain and ejection fraction) based on the standard 16 segment model using our in-house software. HCM patients were further classified into four quartiles based on wall thickness at end diastole (ED) to assess the impact of wall thickness on these regional parameters. There was a significant difference between the HCM patients and controls for all regional parameters (

Indexed as

hypertrophic cardiomyopathymagnetic resonance imagingregional area strainregional curvednessregional wall stress index

Identifiers

PMID29643812
PMCPMC5882847
OpenAlexW2794958457

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.