Evidence map›Paper›PMID 29643710›Full record

ArticleTzu chi medical journal

Positive correlation of serum leptin levels and peripheral arterial stiffness in patients with type 2 diabetes.

Chia-Wen Lu, Chung-Jen Lee, Jia-Sian Hou, Du-An Wu, Bang-Gee Hsu

Abstract read
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In one paragraph

Article in Tzu chi medical journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Adipokines and Arterial Stiffness in Obesity.Medicina (Kaunas, Lithuania) · 2021
    Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chia-Wen LuDepartment of Nursing, Buddhist Tzu Chi General Hospital, Hualien, Taiwan.
Chung-Jen LeeDepartment of Nursing, Tzu Chi University of Science and Technology, Hualien, Taiwan.
Jia-Sian HouDepartment of Nursing, Buddhist Tzu Chi General Hospital, Hualien, Taiwan.
Du-An WuDepartment of Metabolism and Endocrinology, Buddhist Tzu Chi General Hospital, Hualien, Taiwan.
Bang-Gee HsuInstitute of Medical Sciences, Tzu Chi University, Hualien, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveLeptin plays a pathophysiologic role in the pathogenesis of aortic dysfunction and peripheral arterial stiffness (PAS). Our aim was to evaluate the risk factors for developing PAS and the association of leptin and PAS in patients with type 2 diabetes mellitus (DM). MATERIALS AND

methodsFasting blood samples were obtained for biochemical data and leptin determinations from 105 patients with type 2 DM. In this study, we applied an automatic pulse wave analyzer (VaSera VS-1000) to measure the brachial-ankle pulse wave velocity (baPWV); a baPWV value >14.0 m/s on either side was considered high PAS.

resultsSeventy-five patients (71.4%) had high PAS and they included a higher percentage of patients with hypertension (

conclusionThe serum leptin level could be a predictor of PAS in type 2 DM patients.

Indexed as

Brachial-ankle pulse wave velocityLeptinPeripheral arterial stiffnessType 2 diabetes mellitus

Identifiers

PMID29643710
PMCPMC5883830

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.