Evidence map›Paper›PMID 29643557›Full record

ArticleIndian journal of anaesthesia2018

Reversal agents: do we need to administer with neuromuscular monitoring - an observational study.

Shilpa Goyal, Nikhil Kothari, Deepak Chaudhary, Shilpi Verma, Pooja Bihani, Mahaveer Singh Rodha

Open access · diamondAbstract read
In one paragraph

Article in Indian journal of anaesthesia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Reversal of neuromuscular block.Indian journal of anaesthesia · 2018
    Article
  6. Comments on Published Article: A valuable resource.Indian journal of anaesthesia · 2018
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Shilpa GoyalDepartment of Anaesthesiology and Critical Care, AIIMS, Jodhpur, Rajasthan, India.
Nikhil KothariDepartment of Anaesthesiology and Critical Care, AIIMS, Jodhpur, Rajasthan, India.
Deepak ChaudharyDepartment of Anaesthesiology and Critical Care, AIIMS, Jodhpur, Rajasthan, India.
Shilpi VermaDepartment of Anaesthesiology and Critical Care, AIIMS, Jodhpur, Rajasthan, India.
Pooja BihaniDepartment of Anaesthesiology and Critical Care, AIIMS, Jodhpur, Rajasthan, India.
Mahaveer Singh RodhaTrauma and Emergency, AIIMS, Jodhpur, Rajasthan, India.
All India Institute of Medical Sciences Jodhpur · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsIn clinical practice, in the majority of patients, recovery from the effect of muscle relaxants is assessed using subjective methods such as head lift, eye-opening, or by sustained hand grip after giving anticholinesterases (neostigmine) at the end of surgery. We planned a prospective observational cohort study to test the hypothesis that objective neuromuscular monitoring can help us in avoiding the use of anticholinesterases for reversal.

methodsThe patients posted for surgery of <2 h duration were included in the study. The cohort of patients was formed on the basis of those who were exposed to objective neuromuscular monitoring of recovery (train-of-four [TOF] ratio of 0.9 or more; exposed group) and the patients who were not exposed to objective neuromuscular monitoring (non-exposed group) acting as a control. Using objective neuromuscular monitoring, the time required for recovery from muscle relaxation when neostigmine was not given for reversal was noted and it was then compared with that of the control group.

resultsA total of 190 patients were enrolled over a period of 3 years. With the use of TOF ratio of 0.9 for extubation, patients safely recovered from neuromuscular blockade, without using neostigmine, with no difference in the mean recovery time (14.48 ± 1.138 min) as compared to the control group (12.14 ± 1.067 min,

conclusionWith objective neuromuscular monitoring, we can ensure complete recovery from the neuromuscular blockade while avoiding the use of anticholinesterases.

Indexed as

Objective neuromuscular monitoringrecovery durationreversal agents

Identifiers

PMID29643557
PMCPMC5881325
OpenAlexW2790929433

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.