Evidence map›Paper›PMID 29643509›Full record

ArticleNature2018

Structural basis for ATP-dependent chromatin remodelling by the INO80 complex.

Sebastian Eustermann, Kevin Schall, Dirk Kostrewa, Kristina Lakomek, Mike Strauss, Manuela Moldt, Karl-Peter Hopfner

Open access · greenAbstract read
In one paragraph

Article in Nature, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 148 papers.

0numbers the graph read from it
0cells of the map it votes in
148citing papers in PubMed
13.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

148 citing papers in PubMed, 277 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
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  5. Review
  6. Cryo-EM structure of ALC1 in an open conformation bound to a PARylated nucleosome.Acta crystallographica. Section D, Structural biology · 2026
    Article
  7. Article
  8. Mapping Allosteric Communication in the Nucleosome with Conditional Activity.Journal of chemical information and modeling · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Rotational settings quantize nucleosome movement by chromatin regulators.bioRxiv : the preprint server for biology · 2025
    Article
  14. Cohesin Facilitates Nucleosome Invasion by Transcription Factors.bioRxiv : the preprint server for biology · 2025
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Mechanistic insights into INO80-type chromatin remodelers.Current opinion in structural biology · 2025
    Review
  20. Article

88 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sebastian EustermannDepartment of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
Kevin SchallDepartment of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
Dirk KostrewaDepartment of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
Kristina LakomekDepartment of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
Mike StraussMax Planck Institute of Biochemistry, Martinsried, Germany.
Manuela MoldtDepartment of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
Karl-Peter HopfnerDepartment of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany. hopfner@genzentrum.lmu.de.
Ludwig-Maximilians-Universität München · DEMax Planck Institute of Biochemistry · DE

Funding

European Research Council 322869
6 · The paper itself

Abstract

In the eukaryotic nucleus, DNA is packaged in the form of nucleosomes, each of which comprises about 147 base pairs of DNA wrapped around a histone protein octamer. The position and histone composition of nucleosomes is governed by ATP-dependent chromatin remodellers

Indexed as

Chromatin Assembly and DisassemblyCryoelectron MicroscopyAdenosine TriphosphateAmino Acid SequenceChaetomiumChromosomal Proteins, Non-HistoneDNADNA HelicasesFungal ProteinsHistonesHumansModels, MolecularMultiprotein ComplexesNucleosomesProtein BindingSaccharomyces cerevisiae ProteinsAdenosine TriphosphateChromosomal Proteins, Non-HistoneDNADNA HelicasesFungal ProteinsHistonesINO80 complex, S cerevisiaeMultiprotein ComplexesNucleosomesSaccharomyces cerevisiae Proteins

Identifiers

PMID29643509
PMCPMC6071913
OpenAlexW2797631238

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.