Evidence map›Paper›PMID 29643247›Full record

ArticleJournal of virology2018

The Pathway To Establishing HIV Latency Is Critical to How Latency Is Maintained and Reversed.

Simin D Rezaei, Hao K Lu, J Judy Chang, Ajantha Rhodes, Sharon R Lewin, Paul U Cameron

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. The reservoir of latent HIV.Frontiers in cellular and infection microbiology · 2022
    Review
  8. Article
  9. Review
  10. Article
  11. lncRNAs in T lymphocytes: RNA regulation at the heart of the immune response.American journal of physiology. Cell physiology · 2021
    Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. The multifaceted nature of HIV latency.The Journal of clinical investigation · 2020
    Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Simin D RezaeiThe Peter Doherty Institute for Infection and Immunity, The University of Melbourne and Royal Melbourne Hospital, Melbourne, Australia.
Hao K LuThe Peter Doherty Institute for Infection and Immunity, The University of Melbourne and Royal Melbourne Hospital, Melbourne, Australia.
J Judy ChangThe Peter Doherty Institute for Infection and Immunity, The University of Melbourne and Royal Melbourne Hospital, Melbourne, Australia.
Ajantha RhodesThe Peter Doherty Institute for Infection and Immunity, The University of Melbourne and Royal Melbourne Hospital, Melbourne, Australia.
Sharon R LewinThe Peter Doherty Institute for Infection and Immunity, The University of Melbourne and Royal Melbourne Hospital, Melbourne, Australia.
Paul U CameronThe Peter Doherty Institute for Infection and Immunity, The University of Melbourne and Royal Melbourne Hospital, Melbourne, Australia paul.cameron@unimelb.edu.au.ORCID https://orcid.org/0000-0002-1906-6945
The Royal Melbourne Hospital · AU

Funding

Viral reservoirs and sanctuaries in HAART - treated patients: role and mechanismsU19AI096109 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SCHACKER, TIMOTHY W · 2011 to 2015
$29.5M
NIAID NIH HHS U19 AI096109
6 · The paper itself

Abstract

HIV infection requires lifelong antiretroviral therapy because of the persistence of latently infected CD4

Indexed as

Virus ActivationVirus LatencyVirus ReplicationCD4-Positive T-LymphocytesCells, CulturedDNA, ViralGreen Fluorescent ProteinsHIV-1HIV InfectionsHumansLymphocyte ActivationVirus IntegrationDNA, Viralenhanced green fluorescent proteinGreen Fluorescent Proteinshuman immunodeficiency viruslatencymonocytesT cells

Identifiers

PMID29643247
PMCPMC6002734
OpenAlexW2797584216

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.