ArticleJournal of virology2018
Dynamics of Simian Immunodeficiency Virus Two-Long-Terminal-Repeat Circles in the Presence and Absence of CD8
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In one paragraph
Article in Journal of virology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 24 citations in OpenAlex.
- Impact of a factor Xa inhibitor (apixaban) on SIV pathogenesis and response to antiretroviral therapy.JCI insight · 2026Article
- Post-treatment SIV control is associated with specific features of viral persistence before and after treatment interruption.Nature communications · 2026Article
- Dynamics of natural and pharmacologic control of an SIV variant with an envelope trafficking defect.The Journal of experimental medicine · 2026Article
- Modeling simian immunodeficiency virus (SIV) latency in primary rhesus macaque CD4bioRxiv : the preprint server for biology · 2025Article
- Pathogenic SIV infection is associated with acceleration of epigenetic age in rhesus macaques.The Journal of clinical investigation · 2025Article
- Dual blockade of IL-10 and PD-1 leads to control of SIV viral rebound following analytical treatment interruption.Nature immunology · 2024Article
- Biphasic decay of intact SHIV genomes following initiation of antiretroviral therapy complicates analysis of interventions targeting the reservoir.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- CD8Nature communications · 2023Article
- Antiretroviral therapy reveals triphasic decay of intact SIV genomes and persistence of ancestral variants.Cell host & microbe · 2023Article
- Limited impact of fingolimod treatment during the initial weeks of ART in SIV-infected rhesus macaques.Nature communications · 2022Article
- Therapeutic efficacy of an Ad26/MVA vaccine with SIV gp140 protein and vesatolimod in ART-suppressed rhesus macaques.NPJ vaccines · 2022Article
- Ultrasensitive detection and quantification of viral nucleic acids with Raindance droplet digital PCR (ddPCR).Methods (San Diego, Calif.) · 2022Article
- Complex decay dynamics of HIV virions, intact and defective proviruses, and 2LTR circles following initiation of antiretroviral therapy.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Lack of Specific Regulatory T Cell Depletion and Cytoreduction Associated with Extensive Toxicity After Administration of Low and High Doses of Cyclophosphamide.AIDS research and human retroviruses · 2022Article
- Persistence of viral RNA in lymph nodes in ART-suppressed SIV/SHIV-infected Rhesus Macaques.Nature communications · 2021Article
- Increased Proviral DNA in Circulating Cells Correlates with Plasma Viral Rebound in Simian Immunodeficiency Virus-Infected Rhesus Macaques after Antiretroviral Therapy Interruption.Journal of virology · 2021Article
- Review
- Development of a reverse transcription droplet digital PCR (RT-ddPCR) assay for sensitive detection of simian immunodeficiency virus (SIV).Virology journal · 2021Article
- Mucosal integrin α4β7 blockade fails to reduce the seeding and size of viral reservoirs in SIV-infected rhesus macaques.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021Article
- Simian-Human Immunodeficiency Virus SHIV.C.CH505 Persistence in ART-Suppressed Infant Macaques Is Characterized by Elevated SHIV RNA in the Gut and a High Abundance of Intact SHIV DNA in Naive CD4Journal of virology · 2020Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Benjamin B PolicicchioCenter for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Erwing Fabian CardozoTheoretical Biology and Biophysics Group, Los Alamos National Laboratory, Los Alamos, New Mexico, USA.
Paola SetteCenter for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Cuiling XuCenter for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
George Haret-RichterCenter for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Tammy DunsmoreCenter for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Cristian ApetreiCenter for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Ivona PandreaCenter for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, USA pandrea@pitt.edu ruyribeiro@medicina.ulisboa.pt.
Ruy M RibeiroTheoretical Biology and Biophysics Group, Los Alamos National Laboratory, Los Alamos, New Mexico, USA pandrea@pitt.edu ruyribeiro@medicina.ulisboa.pt.
University of Pittsburgh · USLos Alamos National Laboratory · USUniversity of Lisbon · PT
Funding
SIV Pathogenesis in African Green Monkeys and Pigtailed MacaquesR01HL117715 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI VASILE PANDREA, IVONA · 2012 to 2021
$7.0MInterventions to Reduce Hypercoagulability in Old SIV-Infected NHPsR01HL123096 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI VASILE PANDREA, IVONA · 2015 to 2025
$6.8MAnimal Model for Testing SIV Latency Reversal StrategiesR01AI119346 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI APETREI, CRISTIAN · 2015 to 2019
$3.4MPITT AIDS RESEARCH TRAINING PROGRAMT32AI065380 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BARRATT-BOYES, SIMON M · 2005 to 2020
$3.2MQuantifying Immune VS. Viral Killing of SIV Infected and Latently Infected CellsR01AI104373 · NIAID · LOS ALAMOS NAT SECTY-LOS ALAMOS NAT LAB · PI RIBEIRO, RUY M · 2013 to 2016
$2.7MNHLBI NIH HHS R01 HL117715NHLBI NIH HHS R01 HL123096NIAID NIH HHS R01 AI104373NIAID NIH HHS R01 AI119346NIAID NIH HHS T32 AI065380
Abstract
CD8
Indexed as
Terminal Repeat SequencesAnimalsCD8-Positive T-LymphocytesLeukocytes, MononuclearLymph NodesMacaca mulattaSimian Acquired Immunodeficiency SyndromeSimian Immunodeficiency VirusViral LoadVirus Replication2-LTR circlesCD8+ cell depletionintegrase inhibitorraltegravirrhesus macaquessimian immunodeficiency virus
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.