ReviewMicrobiology and molecular biology reviews : MMBR2018
Fungal Morphogenesis, from the Polarized Growth of Hyphae to Complex Reproduction and Infection Structures.
Review in Microbiology and molecular biology reviews : MMBR, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 179 papers.
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Who cites it
179 citing papers in PubMed.
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- Pathogenicity and virulence of the blast fungusVirulence · 2026Review
- The complex subunit VdAP-2α regulates polar growth, ergosterol metabolism, and virulence inVirulence · 2026Article
- Green synthesis of a manganese oxide-selenium nanocomposite using watermelon peel waste with antimicrobial and mosquitocidal activities.RSC advances · 2026Article
- A Systematic Method for Analysing Germination of Aspergillus Conidia Using Real-Time Imaging.Journal of basic microbiology · 2026Article
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- Effect of Low-Frequency Alternating Magnetic Field-Assisted Liquid Fermentation on Extracellular Polysaccharides Structural Characteristics and Biosynthesis ofFoods (Basel, Switzerland) · 2026Article
- From EM to AI: Multiscale imaging of the secretory pathway with insights from plant cells.Journal of microscopy · 2026Review
- Proteomic Evidence Indicates Ultrasound-Assisted Extraction Enhances Recovery of Membrane-Associated Proteins inJournal of agricultural and food chemistry · 2026Article
- Eisosomal proteins are essential for plant-fungal interaction of Neurospora crassa and the sweetgrass Brachypodium distachyon.Scientific reports · 2026Article
- A quantitative framework for multiscale analysis ofBiofilm · 2026Article
- Dynamic Reprogramming of Fungal Cell Walls Underlies Germination and Immune Exposure in Zygomycetous Fungal Pathogens.bioRxiv : the preprint server for biology · 2026Article
- Self-grown mycelium in confined geometries as nanofluidic devices.Nature communications · 2026Article
- The Oligosaccharyltransferase Catalytic Subunit PsSTT3B Is Required for Asexual Development and Pathogenicity inJournal of fungi (Basel, Switzerland) · 2026Article
- Elucidation of the Biological Function and Early-Infection Cell Cycle Regulatory Mechanism of Avocado-InfectingFoods (Basel, Switzerland) · 2026Article
- Dissecting G-protein signaling pathways in the fruit pathogen Penicillium expansum: implications for pathogenesis and patulin production.Molecular horticulture · 2026Article
- Dissecting the RNA-binding capacity of the multi-RRM protein Rrm4 essential for endosomal mRNA transport.Nucleic acids research · 2026Article
- Carbon-phosphorus exchange rate constrains density-speed trade-off in arbuscular mycorrhizal fungal growth.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Glycolysis-dependent sulfur metabolism orchestrates morphological plasticity and virulence in fungi.eLife · 2026Article
- Article
119 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Filamentous fungi constitute a large group of eukaryotic microorganisms that grow by forming simple tube-like hyphae that are capable of differentiating into more-complex morphological structures and distinct cell types. Hyphae form filamentous networks by extending at their tips while branching in subapical regions. Rapid tip elongation requires massive membrane insertion and extension of the rigid chitin-containing cell wall. This process is sustained by a continuous flow of secretory vesicles that depends on the coordinated action of the microtubule and actin cytoskeletons and the corresponding motors and associated proteins. Vesicles transport cell wall-synthesizing enzymes and accumulate in a special structure, the Spitzenkörper, before traveling further and fusing with the tip membrane. The place of vesicle fusion and growth direction are enabled and defined by the position of the Spitzenkörper, the so-called cell end markers, and other proteins involved in the exocytic process. Also important for tip extension is membrane recycling by endocytosis via early endosomes, which function as multipurpose transport vehicles for mRNA, septins, ribosomes, and peroxisomes. Cell integrity, hyphal branching, and morphogenesis are all processes that are largely dependent on vesicle and cytoskeleton dynamics. When hyphae differentiate structures for asexual or sexual reproduction or to mediate interspecies interactions, the hyphal basic cellular machinery may be reprogrammed through the synthesis of new proteins and/or the modification of protein activity. Although some transcriptional networks involved in such reprogramming of hyphae are well studied in several model filamentous fungi, clear connections between these networks and known determinants of hyphal morphogenesis are yet to be established.
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