Evidence map›Paper›PMID 29643150›Full record

SynthesisBMJ open2018

Rate of adherence to urate-lowering therapy among patients with gout: a systematic review and meta-analysis.

Rulan Yin, Lin Li, Guo Zhang, Yafei Cui, Lijuan Zhang, Qiuxiang Zhang, Ting Fu, Haixia Cao, Liren Li, Zhifeng Gu

Registry-linked trialAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07061587 (Developing A Gout Action Plan in Primary Care Setting in Singapore), which is not on this map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07061587 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Developing A Gout Action Plan in Primary Care Setting in Singapore

TypeinterventionalSponsorSingHealth PolyclinicsRan2025 to 2027Enrolled72ConditionsGout, Hyperuricemia, Gout Flare, Gout ChronicArmsGout action plan
3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Endoscopic management of lumbar spinal tophaceous gout: six cases treated with percutaneous transforaminal (PTED) and interlaminar (PIED) discectomy and a literature review.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Review
  7. Article
  8. Quality Care Assessment in Gout.Current rheumatology reports · 2025
    Review
  9. Observational
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Current state and prospects of gout treatment in Korea.The Korean journal of internal medicine · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rulan Yin *Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong, China.
Lin Li *School of Nursing, Nantong University, Nantong, China.
Guo Zhang *Department of Operating Room, The First Affiliated Hospital of Soochow University, Suzhou, China.
Yafei CuiSchool of Nursing, Nantong University, Nantong, China.
Lijuan ZhangSchool of Nursing, Nantong University, Nantong, China.
Qiuxiang ZhangSchool of Nursing, Nantong University, Nantong, China.
Ting FuResearch Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong, China.
Haixia CaoDepartment of Rheumatology, Affiliated Hospital of Nantong University, Nantong, China.
Liren LiSchool of Nursing, Nantong University, Nantong, China.
Zhifeng GuResearch Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionReported adherence to urate-lowering therapy (ULT) in gout varies widely (17%-83.5%). Variability may partly be due to different adherence measurement methods. This review aimed to quantify ULT adherence in adult patients with gout.

methodsThis analysis examined studies in PubMed, Web of Science, CNKI Scholar and WanFang databases from inception to January 2017. Papers were selected by inclusion and exclusion criteria in the context. Random-effect meta-analysis estimated adherence.

results22 studies were found by the inclusion criteria, which involved 1 37 699 patients with gout. Four ways to define adherence were reported. Meta-analysis revealed that the overall adherence rate was 47% (95% CI 42% to 52%, I

conclusionsAmong adult patients with gout, overall adherence rate to ULT was as low as 47%, which suggested that clinicians should pay more attention to medication adherence in patients with gout to effectively improve adherence to ULT.

Indexed as

Medication AdherenceAdultAgedCross-Sectional StudiesFemaleGoutGout SuppressantsHumansLongitudinal StudiesMaleMiddle AgedUric AcidGout SuppressantsUric Acidadherencegoutmeta-analysisurate-lowering therapy

Identifiers

PMID29643150
PMCPMC5898304

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.