ArticleBMJ case reports2018
Orbital metastasis from an occult breast carcinoma (T0, N1, M1).
Article in BMJ case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 10 citations in OpenAlex.
- Orbital metastasis from breast carcinoma: structured literature review and report of four cases.Frontiers in ophthalmology · 2026Article
- Case Report: Synchronous cervical, gastric and rectal metastases in occult breast cancer.Frontiers in oncology · 2025Article
- General characteristics of orbital metastasis in breast cancer: a narrative review of case reports.International cancer conference journal · 2024Review
- Loss of E-cadherin leads to Id2-dependent inhibition of cell cycle progression in metastatic lobular breast cancer.Oncogene · 2022Article
- A 'never miss' diagnosis: Ptosis secondary to metastatic breast cancer diagnosed as involutional ptosis and a review of the literature.SAGE open medical case reports · 2021Article
- Rare sites of breast cancer metastasis: a review.Translational cancer research · 2019Review
- Unique presentation of occult breast cancer with uterine cervix metastasis.Clinical case reports · 2019Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The authors report a case of an orbital metastasis from an occult breast carcinoma. A 66-year-old woman presented with a growing left orbital tumour. Orbital CT scan was consistent with lymphoma. However, ocular pathology revealed small neoplastic cells showing an 'indian file pattern' suggestive of metastatic carcinoma and immunohistochemistry was positive for CK7, CK CAM5.2 and oestrogen receptor. A systemic evaluation was then performed with mammogram, breast ultrasound and MRI considered normal. An exhaustive systemic evaluation revealed multiple bone lesions, a right axillary lymph node lesion, which presented the same pattern on pathology and immunohistochemistry, with no evidence of a primary tumour. A diagnosis of a metastatic lobular carcinoma of the breast (T0, N1, M1) was made and the patient was started on chemotherapy and adjuvant hormonal therapy.
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Registered trials
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