Evidence map›Paper›PMID 29643105›Full record

Trial reportBlood advances2018

A next-generation sequencing-based assay for minimal residual disease assessment in AML patients with

Mark J Levis, Alexander E Perl, Jessica K Altman, Christopher D Gocke, Erkut Bahceci, Jason Hill, Chaofeng Liu, Zhiyi Xie, Andrew R Carson, Valerie McClain and 2 more

Open access · goldAbstract readClinical Trial, Phase IClinical Trial, Phase II
In one paragraph

Trial report in Blood advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed
11.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 144 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Gilteritinib as Post-Transplant Maintenance for AML With Internal Tandem Duplication Mutation ofJournal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024
    Trial
  7. FLT3-Mutated AML: Transplanting with Precision in the Targeted Era.Current hematologic malignancy reports · 2026
    Review
  8. Article
  9. FLT3-ITD MRD is here to stay.Blood advances · 2026
    Article
  10. Article
  11. Article
  12. Cancers · 2026
    Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article

25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Mark J LevisSidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD.
Alexander E PerlUniversity of Pennsylvania-Abramson Comprehensive Cancer Center, Philadelphia, PA.
Jessica K AltmanRobert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL.
Christopher D GockeSidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD.
Erkut BahceciAstellas Pharma Global Development, Northbrook, IL; and.
Jason HillAstellas Pharma Global Development, Northbrook, IL; and.
Chaofeng LiuAstellas Pharma Global Development, Northbrook, IL; and.
Zhiyi XieInvivoscribe, Inc, San Diego, CA.
Andrew R CarsonInvivoscribe, Inc, San Diego, CA.
Valerie McClainInvivoscribe, Inc, San Diego, CA.
Timothy T StenzelInvivoscribe, Inc, San Diego, CA.
Jeffrey E MillerInvivoscribe, Inc, San Diego, CA.
Astellas Pharma (United States) · USJohns Hopkins University · USNorthwestern University · USSidney Kimmel Comprehensive Cancer Center · USUniversity of Pennsylvania · US

Funding

University of Texas M.D. Anderson Cancer SPORE-LeukemiaP50CA100632 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI SHPALL, ELIZABETH J · 2003 to 2023
$43.7M
The Johns Hopkins Translational Science Team for the ET-CTNUM1CA186691 · NCI · JOHNS HOPKINS UNIVERSITY · PI Jan Hendrik Beumer, Michael A Carducci · 2014 to 2026
$21.9M
Wisconsin and New Jersey Alliance in Precision Experimental TherapeuticsUM1CA186716 · NCI · RBHS -CANCER INSTITUTE OF NEW JERSEY · PI JABBOUR, SALMA, LIU, GLENN · 2014 to 2019
$4.1M
NCI NIH HHS P50 CA100632NCI NIH HHS UM1 CA186691NCI NIH HHS UM1 CA186716
6 · The paper itself

Abstract

Internal tandem duplications in

Indexed as

Aniline CompoundsBone Marrowfms-Like Tyrosine Kinase 3High-Throughput Nucleotide SequencingHumansLeukemia, Myeloid, AcuteNeoplasm, ResidualPyrazinesSurvival RateTandem Repeat SequencesAniline CompoundsFLT3 protein, humanfms-Like Tyrosine Kinase 3gilteritinibPyrazines

Identifiers

PMID29643105
PMCPMC5916006
OpenAlexW2798041034

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.