Evidence map›Paper›PMID 29643076›Full record

ArticlemSphere2018

High Salt Cross-Protects

Manlu Zhu, Xiongfeng Dai

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in mSphere, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.0field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Tradeoffs in bacterial physiology determine the efficiency of antibiotic killing.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. NaCl Concentration-Dependent Aminoglycoside Resistance ofJournal of microbiology and biotechnology · 2021
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Manlu ZhuSchool of Life Sciences, Central China Normal University, Wuhan, China zhumanlu@mail.ccnu.edu.cn daixiongfeng@mail.ccnu.edu.cn.
Xiongfeng DaiSchool of Life Sciences, Central China Normal University, Wuhan, China zhumanlu@mail.ccnu.edu.cn daixiongfeng@mail.ccnu.edu.cn.
Central China Normal University · CN

Funding

Quantitative Studies of Bacterial Growth PhysiologyR01GM095903 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HWA, TERENCE · 2011 to 2023
$3.8M
NIGMS NIH HHS R01 GM095903
6 · The paper itself

Abstract

Environmental stresses often co-occur when bacteria encounter antibiotic treatment inside the human body. The cellular response to environmental stressors can alter the global gene expression pattern of bacteria. However, the relationship between the cellular stress response and antibiotic susceptibility remains poorly understood. Here we studied the effect of high salt, an important environmental stress condition inside the human body, on bacterial susceptibility to antibiotics. We found that high salt reduces the susceptibility of

Indexed as

Anti-Bacterial AgentsBacterial Outer Membrane ProteinsChloramphenicolEscherichia coliGene Expression Regulation, BacterialMembrane Transport ProteinsSodium ChlorideTetracyclineAnti-Bacterial AgentsBacterial Outer Membrane ProteinsChloramphenicolMembrane Transport ProteinsSodium ChlorideTetracyclineantibiotic susceptibilitycross-protectionefflux pumpshigh salt

Identifiers

PMID29643076
PMCPMC5909119
OpenAlexW2797886355

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.