Evidence map›Paper›PMID 29642720›Full record

ArticleAmerican journal of Alzheimer's disease and other dementias2018

Use of Potentially Inappropriate Medications in People With Dementia in Vietnam and Its Associated Factors.

Tuan Anh Nguyen, Thang Pham, Huyen Thi Thanh Vu, Thanh Xuan Nguyen, Trinh Thi Vu, Binh Thi Thanh Nguyen, Ngoc Quynh Nguyen, Binh Thanh Nguyen, Binh Thanh Nguyen, Tam Ngoc Nguyen and 15 more

Abstract read
In one paragraph

Article in American journal of Alzheimer's disease and other dementias, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Tuan Anh Nguyen1 Quality Use of Medicines and Pharmacy Research Centre, School of Pharmacy and Medical Sciences, Sansom Institute for Health Research, University of South Australia, Adelaide, South Australia, Australia.ORCID 0000-0002-9528-9278
Thang Pham2 National Geriatric Hospital of Vietnam, Hanoi, Vietnam.
Huyen Thi Thanh Vu2 National Geriatric Hospital of Vietnam, Hanoi, Vietnam.
Thanh Xuan Nguyen2 National Geriatric Hospital of Vietnam, Hanoi, Vietnam.
Trinh Thi Vu2 National Geriatric Hospital of Vietnam, Hanoi, Vietnam.
Binh Thi Thanh Nguyen2 National Geriatric Hospital of Vietnam, Hanoi, Vietnam.
Ngoc Quynh Nguyen2 National Geriatric Hospital of Vietnam, Hanoi, Vietnam.
Binh Thanh Nguyen2 National Geriatric Hospital of Vietnam, Hanoi, Vietnam.
Binh Thanh Nguyen2 National Geriatric Hospital of Vietnam, Hanoi, Vietnam.
Tam Ngoc Nguyen2 National Geriatric Hospital of Vietnam, Hanoi, Vietnam.
Sinh Viet Phan2 National Geriatric Hospital of Vietnam, Hanoi, Vietnam.
Anh Trung Nguyen2 National Geriatric Hospital of Vietnam, Hanoi, Vietnam.
Tuan Le Pham3 Hanoi Medical University and Ministry of Health of Vietnam, Hanoi, Vietnam.
Ha Thu Dang1 Quality Use of Medicines and Pharmacy Research Centre, School of Pharmacy and Medical Sciences, Sansom Institute for Health Research, University of South Australia, Adelaide, South Australia, Australia.
Lisa Kalisch-Ellett1 Quality Use of Medicines and Pharmacy Research Centre, School of Pharmacy and Medical Sciences, Sansom Institute for Health Research, University of South Australia, Adelaide, South Australia, Australia.
Marianne Gillam1 Quality Use of Medicines and Pharmacy Research Centre, School of Pharmacy and Medical Sciences, Sansom Institute for Health Research, University of South Australia, Adelaide, South Australia, Australia.
Nicole Pratt1 Quality Use of Medicines and Pharmacy Research Centre, School of Pharmacy and Medical Sciences, Sansom Institute for Health Research, University of South Australia, Adelaide, South Australia, Australia.
Sun Qiang4 Center for Health Management and Policy, School of Health Care Management, Shandong University, Jinan, China.
Haipeng Wang4 Center for Health Management and Policy, School of Health Care Management, Shandong University, Jinan, China.
Tipaporn Kanjanarach5 Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen, Thailand.
Mohamed Azmi Ahmad Hassali6 School of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, Malaysia.
Zaheer-Ud-Din Babar7 Department of Pharmacy, University of Huddersfield, England, United Kingdom.
Asrenee Ab Razak8 Department of Psychiatry, School of Medical Sciences, Universiti Sains Malaysia, Penang, Malaysia.
Dujrudee Chinwong9 Department of Pharmaceutical Care, Faculty of Pharmacy, Chiang Mai University, Chiang Mai, Thailand.
Elizabeth E Roughead1 Quality Use of Medicines and Pharmacy Research Centre, School of Pharmacy and Medical Sciences, Sansom Institute for Health Research, University of South Australia, Adelaide, South Australia, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study examined the use of potentially inappropriate medicines that may affect cognition (PIMcog) in people with dementia and its associated factors. Medical records of all outpatients with dementia attending a tertiary hospital in Vietnam between January 1, 2015, and December 31, 2016, were examined. Medicine use was assessed against a list of PIMcog. Variables associated with having a PIMcog were assessed using a multiple logistic regression. Of the 128 patients, 41% used a PIMcog, 39.1% used cholinesterase inhibitors (CEIs) concomitantly with anticholinergics, and 18% used antipsychotics. The number of hospital visits (adjusted odds ratio [OR]: 1.08; 95% confidence interval [CI]: 1.02-1.16) and number of treating specialists (adjusted OR: 0.61; 95% CI: 0.45-0.83) were associated with PIMcog use. This study highlights a high-level use of medicines that can further impair cognition or reduce the effectiveness of CEIs in people with dementia. Efforts to improve quality use of medicines for this population are warranted.

Indexed as

AgedAged, 80 and overAntipsychotic AgentsCholinergic AntagonistsCholinesterase InhibitorsCognitionDementiaFemaleHumansMalePotentially Inappropriate Medication ListVietnamAntipsychotic AgentsCholinergic AntagonistsCholinesterase Inhibitorsanticholinergicsantipsychoticsdementiapotentially inappropriate medicinesquality use of medicinessedatives

Identifiers

PMID29642720
PMCPMC10852524

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.