Evidence map›Paper›PMID 29642698›Full record

ArticleThe journal of physical chemistry letters2018

Single-Molecule Test for Markovianity of the Dynamics along a Reaction Coordinate.

Alexander M Berezhkovskii, Dmitrii E Makarov

Abstract read
In one paragraph

Article in The journal of physical chemistry letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Hierarchical friction memory leads to subdiffusive configurational dynamics of fast-folding proteins.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Article
  4. General theory for localizing the where and when of entropy production meets single-molecule experiments.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  5. Milestoning estimators of dissipation in systems observed at a coarse resolution.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  6. Fast protein folding is governed by memory-dependent friction.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  7. A universal description of stochastic oscillators.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  8. Microcanonical coarse-graining of the kinetic Ising model.The Journal of chemical physics · 2020
    Article
  9. Measuring the average shape of transition paths during the folding of a single biological molecule.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Alexander M BerezhkovskiiMathematical and Statistical Computing Laboratory, Office of Intramural Research, Center for Information Technology , National Institutes of Health , Bethesda , Maryland 20892 , United States.
Dmitrii E MakarovDepartment of Chemistry , University of Texas at Austin , Austin , Texas 78712 , United States.ORCID http://orcid.org/0000-0002-8421-1846

Funding

Modeling of kinetic processes in biological systemsZIACT000273 · CIT · CENTER FOR INFORMATION TECHNOLOGY · PI BEREZHKOVSKII, ALEXANDER · 2009 to 2021
$2.1M
Intramural NIH HHS ZIA CT000273
6 · The paper itself

Abstract

In an effort to answer the much-debated question of whether the time evolution of common experimental observables can be described as one-dimensional diffusion in the potential of mean force, we propose a simple criterion that allows one to test whether the Markov assumption is applicable to a single-molecule trajectory x( t). This test does not involve fitting of the data to any presupposed model and can be applied to experimental data with relatively low temporal resolution.

Identifiers

PMID29642698
PMCPMC6748041

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.