Evidence map›Paper›PMID 29642630›Full record

ArticleInternational journal of molecular sciences2018

Aging and Intermittent Fasting Impact on Transcriptional Regulation and Physiological Responses of Adult Drosophila Neuronal and Muscle Tissues.

Sharon Zhang, Eric P Ratliff, Brandon Molina, Nadja El-Mecharrafie, Jessica Mastroianni, Roxanne W Kotzebue, Madhulika Achal, Ruth E Mauntz, Arysa Gonzalez, Ayeh Barekat and 6 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. The Influence of Cannabinoids onCannabis and cannabinoid research · 2024
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. The aging transcriptome: read between the lines.Current opinion in neurobiology · 2020
    Review
  11. Article
  12. Article
  13. The Neuronal Overexpression ofFrontiers in genetics · 2019
    Article
  14. Molecular and Cellular Mechanisms of Aging and Age-related Disorders.International journal of molecular sciences · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Sharon ZhangDonald P. Shiley BioScience Center, San Diego State University, San Diego, CA 92182, USA. sharonzh10@yahoo.com.
Eric P RatliffDonald P. Shiley BioScience Center, San Diego State University, San Diego, CA 92182, USA. epratliff@hotmail.com.
Brandon MolinaDonald P. Shiley BioScience Center, San Diego State University, San Diego, CA 92182, USA. Brandonrm.16@gmail.com.
Nadja El-MecharrafieDonald P. Shiley BioScience Center, San Diego State University, San Diego, CA 92182, USA. nadjaelm@outlook.com.
Jessica MastroianniDonald P. Shiley BioScience Center, San Diego State University, San Diego, CA 92182, USA. jmfmastroianni@yahoo.com.
Roxanne W KotzebueDonald P. Shiley BioScience Center, San Diego State University, San Diego, CA 92182, USA. rkotzebue@gmail.com.
Madhulika AchalDonald P. Shiley BioScience Center, San Diego State University, San Diego, CA 92182, USA. madhulika.achal@gmail.com.
Ruth E MauntzDonald P. Shiley BioScience Center, San Diego State University, San Diego, CA 92182, USA. rmauntz@gmail.com.
Arysa GonzalezDonald P. Shiley BioScience Center, San Diego State University, San Diego, CA 92182, USA. gonzalez.arysa@gmail.com.
Ayeh BarekatDonald P. Shiley BioScience Center, San Diego State University, San Diego, CA 92182, USA. ayeh.sdsu@gmail.com.
William A BrayDonald P. Shiley BioScience Center, San Diego State University, San Diego, CA 92182, USA. yossarianassyrian@gmail.com.
Andrew M MaciasDonald P. Shiley BioScience Center, San Diego State University, San Diego, CA 92182, USA. maciasandrew01@gmail.com.
Daniel DaughertyThe Salk Institute for Biological Studies, Cellular Neurobiology, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA. ddaugherty@salk.edu.
Greg L HarrisDepartment of Biology, San Diego State University, San Diego, CA 92182, USA. gharris@sdsu.edu.
Robert A EdwardsBiological and Medical Informatics Research Center, San Diego State University, San Diego, CA 92182, USA. redwards@sdsu.edu.
Kim D FinleyDonald P. Shiley BioScience Center, San Diego State University, San Diego, CA 92182, USA. kfinley@sdsu.edu.
San Diego State University · USSalk Institute for Biological Studies · USSanford Consortium for Regenerative Medicine · US

Funding

Age-dependent regulation of clearance and signaling pathwaysR01AG039628 · NIA · SAN DIEGO STATE UNIVERSITY · PI FINLEY, KIM D. · 2011 to 2015
$1.5M
Identifying Drugs to Treat Age-Dependent NeurodegenerationR44AG033427 · NIA · EXPRESSION DRUG DESIGNS, LLC · PI FINLEY, KIM D. · 2011 to 2012
$1.3M
Genetic Analysis of Autophagy in the Drosophila Nervous SystemR21AG030187 · NIA · SAN DIEGO STATE UNIVERSITY · PI FINLEY, KIM D. · 2008 to 2009
$349k
NIA NIH HHS R01 AG039628NIA NIH HHS R21 AG030187NIA NIH HHS R44 AG033427
6 · The paper itself

Abstract

The progressive decline of the nervous system, including protein aggregate formation, reflects the subtle dysregulation of multiple functional pathways. Our previous work has shown intermittent fasting (IF) enhances longevity, maintains adult behaviors and reduces aggregates, in part, by promoting autophagic function in the aging

Indexed as

TranscriptomeAgingAnimalsDrosophilaFastingGene Expression Regulation, DevelopmentalMuscle, SkeletalNeuronsProteolysisagingaging-delaying interventionscellular proteostasisDrosophilaintermittent fastingmetabolismneural degenerationRNA-sequencing

Identifiers

PMID29642630
PMCPMC5979431
OpenAlexW2796970858

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.