ArticleGenes2018
Alteration of Hepatic Gene Expression along with the Inherited Phenotype of Acquired Fatty Liver in Chicken.
Article in Genes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- Effects of microalgae supplementation on performance, egg quality, yolk fatty acid levels, and blood parameters in laying hens: a meta-analysis.Scientific reports · 2025Pooled it
- Combined supplementation with Bacillus subtilis and tea polyphenols alleviates high-fat diet-induced fatty liver hemorrhagic syndrome in laying hens by regulating the gut-liver axis.Poultry science · 2026Article
- Protective Effects ofAnimals : an open access journal from MDPI · 2026Article
- Non-Alcoholic Fatty Liver Disease in Poultry: Risk Factors, Mechanism of Development, and Emerging Strategies.International journal of molecular sciences · 2025Review
- Hepatoprotective effects of magnolol in fatty liver hemorrhagic syndrome hens through shaping gut microbiota and tryptophan metabolic profile.Journal of animal science and biotechnology · 2024Article
- Reorganization of 3D genome architecture provides insights into pathogenesis of early fatty liver disease in laying hens.Journal of animal science and biotechnology · 2024Article
- Cross-species analysis of differential transcript usage in humans and chickens with fatty liver disease.Veterinary world · 2023Article
- Flaxseed Reduces Cancer Risk by Altering Bioenergetic Pathways in Liver: Connecting SAM Biosynthesis to Cellular Energy.Metabolites · 2023Article
- Hepatic steatosis is associated with dysregulated cholesterol metabolism and altered protein acetylation dynamics in chickens.Journal of animal science and biotechnology · 2023Article
- Multi-tissue transcriptome analysis to identify candidate genes associated with weight regulation in Hanwoo cattle.Frontiers in genetics · 2023Article
- Real-time assessment of liver fat content using a filter-based Raman system operating under ambient light through lock-in amplification.Biomedical optics express · 2022Article
- GR-mediated transcriptional regulation of mJournal of animal science and biotechnology · 2021Article
- Absence of Circadian Rhythm in Fecal Microbiota of Laying Hens under Common Light.Animals : an open access journal from MDPI · 2021Article
- A novel chicken model of fatty liver disease induced by high cholesterol and low choline diets.Poultry science · 2021Article
- Paternal Dietary Methionine Supplementation Improves Carcass Traits and Meat Quality of Chicken Progeny.Animals : an open access journal from MDPI · 2021Article
- Integrated analysis of the methylome and transcriptome of chickens with fatty liver hemorrhagic syndrome.BMC genomics · 2021Article
- Osteocalcin prevents insulin resistance, hepatic inflammation, and activates autophagy associated with high-fat diet-induced fatty liver hemorrhagic syndrome in aged laying hens.Poultry science · 2021Article
- Maternal dietary methionine supplementation influences egg production and the growth performance and meat quality of the offspring.Poultry science · 2020Article
- Genome-Wide Detection of Key Genes and Epigenetic Markers for Chicken Fatty Liver.International journal of molecular sciences · 2020Article
- Developmental changes in hepatic lipid metabolism of chicks during the embryonic periods and the first week of posthatch.Poultry science · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fatty liver is a widespread disease in chickens that causes a decrease in egg production and even death. The characteristics of the inherited phenotype of acquired fatty liver and the molecular mechanisms underlying it, however, are largely unknown. In the current study, fatty liver was induced in 3 breeds by a high-fat (HF) diet and a methionine choline-deficient (MCD) diet. The results showed that the dwarf Jingxing-Huang (JXH) chicken was more susceptible to fatty liver compared with the layer White Leghorns (WL) and local Beijing-You (BJY) breeds. In addition, it was found that the paternal fatty livers induced by HF diet in JXH chickens were inherited. Compared to birds without fatty liver in the control group, both offsprings and their sires with fatty livers in the paternal group exhibited altered hepatic gene expression profiles, including upregulation of several key genes involved in fatty acid metabolism, lipid metabolism and glucose metabolism (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.