ReviewInternational journal of molecular sciences2018
Antibacterial Free Fatty Acids and Monoglycerides: Biological Activities, Experimental Testing, and Therapeutic Applications.
Review in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 251 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
251 citing papers in PubMed, 1 synthesis or guideline pooled it, 594 citations in OpenAlex.
- Behavioral responses of pigs to dietary alternatives to antibiotic growth promoters: a systematic review.Veterinary research communications · 2026Pooled it
- Milk phospholipid-coated lipid droplets modulate the infant gut microbiota and metabolome influencing weight gain.Microbiome · 2025Trial
- Synergistic antibacterial activity and mechanism of arginine combined with florfenicol againstVirulence · 2026Article
- Differences in lipids and antibacterial activities among three chemotypes ofFood chemistry: X · 2026Article
- Fatty Acid Composition of Fixed Oil of Linum strictum and Its Antibiofilm, Anticoagulant, and α-Amylase Inhibitory Effects-In Vitro and In Silico Study.Chemistry & biodiversity · 2026Article
- Pharmacological basis for the traditional use ofJournal of traditional and complementary medicine · 2026Article
- Saturated fatty acids enhance daptomycin activity in a Fak-dependent manner in enterococci.Microbiology (Reading, England) · 2026Article
- Integrated Phytochemical Profiling, Spectroscopic Analysis, and Molecular Docking Evaluation of Ethanolic Plant Extracts Against Candida Receptor (1IYK).Journal of fungi (Basel, Switzerland) · 2026Article
- Chemical Profiling and In Vitro Assessment of Antioxidant and Antimicrobial Properties of Algerian Erica arborea L. Extracts, Strengthened by Molecular Modeling Analysis.ChemistryOpen · 2026Article
- Article
- Antimicrobial activity of Weissella cibaria strains and the contribution of organic acids against food-associated target microorganisms.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026Article
- Novel antibiofilm strategies against Pseudomonas aeruginosa NG4 using oleic acid and indole-3-butyric acid.Archives of microbiology · 2026Article
- Phytochemical Analysis and Bioactivities ofPlants (Basel, Switzerland) · 2026Article
- Aquatic-derived Streptomyces cavourensis BA1 as a promising source of antibacterial metabolites against multidrug-resistant gram-negative pathogens.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026Article
- Exploring Antimicrobial Activities of Fixed Oil From Sanguisorba minor Seeds by In Vitro and In Silico Analysis.ChemistryOpen · 2026Article
- Phytogenic feed additive mitigates necrotic enteritis-associated gut damage and performance loss in broilers.Poultry science · 2026Article
- Monocaprin, Monolaurin, and Monomyristin EradicatePharmaceuticals (Basel, Switzerland) · 2026Article
- Modifying Effect of the Antibiotic Action, Membrane Permeability, and ADMET/Toxicity Profile of the Fixed Oil From the Pulp of Mauritia Flexuosa F.L. (Arecaceae).Chemistry & biodiversity · 2026Article
- Proangiogenic and Collagen-Promoting Effects of a 70% Ethanol Extract ofInternational journal of molecular sciences · 2026Article
- NMR Based Real-Time Analysis of Exometabolites Decodes the Mechanism of Action of Antibacterial Molecules, Nanoparticles, and Materials.Analytical chemistry · 2026Article
191 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Antimicrobial lipids such as fatty acids and monoglycerides are promising antibacterial agents that destabilize bacterial cell membranes, causing a wide range of direct and indirect inhibitory effects. The goal of this review is to introduce the latest experimental approaches for characterizing how antimicrobial lipids destabilize phospholipid membranes within the broader scope of introducing current knowledge about the biological activities of antimicrobial lipids, testing strategies, and applications for treating bacterial infections. To this end, a general background on antimicrobial lipids, including structural classification, is provided along with a detailed description of their targeting spectrum and currently understood antibacterial mechanisms. Building on this knowledge, different experimental approaches to characterize antimicrobial lipids are presented, including cell-based biological and model membrane-based biophysical measurement techniques. Particular emphasis is placed on drawing out how biological and biophysical approaches complement one another and can yield mechanistic insights into how the physicochemical properties of antimicrobial lipids influence molecular self-assembly and concentration-dependent interactions with model phospholipid and bacterial cell membranes. Examples of possible therapeutic applications are briefly introduced to highlight the potential significance of antimicrobial lipids for human health and medicine, and to motivate the importance of employing orthogonal measurement strategies to characterize the activity profile of antimicrobial lipids.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.