Evidence map›Paper›PMID 29642406›Full record

ArticleMarine drugs2018

Fucoidan Rescues p-Cresol-Induced Cellular Senescence in Mesenchymal Stem Cells via FAK-Akt-TWIST Axis.

Jun Hee Lee, Chul Won Yun, Jin Hur, Sang Hun Lee

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. The role of NADnpj metabolic health and disease · 2025
    Review
  5. Review
  6. Antiphotoaging effects of solvent fractions isolated fromBiochemistry and biophysics reports · 2024
    Article
  7. Review
  8. Effects of p-cresol, a uremic toxin, on cancer cells.Translational cancer research · 2023
    Article
  9. Cellular senescence in brain aging and cognitive decline.Frontiers in aging neuroscience · 2023
    Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. Effects ofInternational journal of molecular sciences · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Jun Hee LeeDepartment of Pharmacology and Toxicology, University of Alabama at Birmingham School of Medicine, Birmingham, AL 35294, USA. j-school@hanmail.net.
Chul Won YunMedical Science Research Institute, Soonchunhyang University Seoul Hospital, Seoul 04401, Korea. skydbs113@naver.com.
Jin HurCenter for Medical Innovation, Seoul National University Hospital, Seoul 03080, Korea. gene44@hanmail.net.
Sang Hun LeeMedical Science Research Institute, Soonchunhyang University Seoul Hospital, Seoul 04401, Korea. ykckss1114@nate.com.ORCID 0000-0002-6713-8229
Soonchunhyang University · KRSeoul National University Hospital · KRUniversity of Alabama at Birmingham · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mesenchymal stem cells (MSCs) are a source for cell-based therapy. Although MSCs have the potential for tissue regeneration, their therapeutic efficacy is restricted by the uremic toxin,

Indexed as

Cell CycleCell ProliferationCells, CulturedCellular SenescenceCresolsFocal Adhesion Kinase 1HumansMesenchymal Stem CellsMesenchymal Stem Cell TransplantationNuclear ProteinsPolysaccharidesProto-Oncogene Proteins c-aktPrPC ProteinsRenal Insufficiency, ChronicSignal TransductionTwist-Related Protein 14-cresolCresolsFocal Adhesion Kinase 1fucoidanNuclear ProteinsPolysaccharidesProto-Oncogene Proteins c-aktPrPC ProteinsPTK2 protein, humanTWIST1 protein, humanTwist-Related Protein 1cellular senescencechronic kidney diseasefucoidanmesenchymal stem cellsp-cresol

Identifiers

PMID29642406
PMCPMC5923408
OpenAlexW2795769491

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.