Evidence map›Paper›PMID 29642226›Full record

ReviewMedicine2018

Clinical features and prognosis of paraquat poisoning in French Guiana: A review of 62 cases.

Narcisse Elenga, Caroline Merlin, Rémi Le Guern, Rémi Kom-Tchameni, Yves-Marie Ducrot, Maxime Pradier, Balthazar Ntab, Kim-Anh Dinh-Van, Milko Sobesky, Daniel Mathieu and 4 more

Abstract readReview
In one paragraph

Review in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  9. A Prospective Study to Assess the Profile and Outcome of Acute Paraquat Poisoning in a Tertiary Care Hospital of West Bengal.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Narcisse ElengaService de Médecine et Chirurgie Pédiatrique, Centre Hospitalier de Cayenne, Rue des flamboyants, Cayenne Cedex, Guyane Française Université de Lille, UFR Médecine CHU Lille, Infection Control EA 7366, Pseudomonas aeruginosa Host-Pathogen Translational Research Group, Lille Département des centres délocalisés de prévention et de soins, Rue des flamboyants, Cayenne Cedex, Guyane Française Service de maladies infctieueses et du voyageur, Centre Hospitalier de Tourcoing-Hôpital Gustave Dron - 135, Tourcoing Département de l'information médicale, Centre Hospitalier de l'Ouest Guyane "Franck Joly"16 avenue du Général de Gaulle, Saint-Laurent-du-Maroni Département de l'information médicale, Centre Médico-chirurgical de Kourou, Kourou Département de l'information médicale, Centre Hospitalier de Cayenne, Rue des flamboyants, Cayenne Cedex, Guyane Française Service de Réanimation Médicale et Médecine Hyperbare, Hôpital Albert Calmette, Lille Cedex Service de néphrologie Service de urgences -SAMU Service de réanimation polyvalente, Centre Hospitalier de Cayenne, Rue des flamboyants, Cayenne Cedex, Guyane Française Centre anti pison, Centre Hospitalier Régional Universitaire de Lille, 2, Lille Cedex, France.
Caroline Merlin
Rémi Le Guern
Rémi Kom-Tchameni
Yves-Marie Ducrot
Maxime Pradier
Balthazar Ntab
Kim-Anh Dinh-Van
Milko Sobesky
Daniel Mathieu
Jean-Marc Dueymes
Gérald Egmann
Hatem Kallel
Monique Mathieu-Nolf

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paraquat is a nonselective contact herbicide of great toxicological importance, being associated with high mortality rates. Because of its high toxicity, the European Union withdrew it from its market in 2007. The aim of this study is to analyze all cases of paraquat poisoning hospitalized in French Guiana in order to assess their incidence and main characteristics.Medical records of all paraquat intoxicated patients hospitalized from 2008 until 2015 were reviewed in this retrospective study.Demographics, clinical presentation, and laboratory data were evaluated.A total of 62 cases were reviewed. The incidence of paraquat poisoning was 3.8/100,000 inhabitants/year. There were 44 adults and 18 children younger than 16 years of age. The median ages were 31 years [18.08-75.25] in adults and 13.4 years [0.75-15.08] in children, respectively. The median duration of hospitalization was longer in children [15.5 days (1-24)] than in adults [2 days (1-30)], P < .01. The majority of cases was due to self-poisoning (84%).Children had ingested a lower quantity of paraquat [48.8 mg/kg (10-571.1)] than adults [595.8 mg/kg (6-3636.4), P = .03]. There were more deaths among adults (65%) than in children (22%), P = .004. The severity and outcome was determined primarily by the amount of paraquat ingested.In conclusion, French Guiana has the largest cohort of paraquat poisonings in the European Union. The major factor affecting the prognosis of patients was the ingested amount of paraquat. The administration of activated charcoal or Pemba, in situ, within the first hour after ingestion of paraquat is essential.

Indexed as

AdolescentAdultAgedCharcoalChildChild, PreschoolDose-Response Relationship, DrugDrug OverdoseFemaleFrench GuianaHumansIncidenceInfantLength of StayMaleMiddle AgedCharcoalParaquat

Identifiers

PMID29642226
PMCPMC5908553

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.