ArticleMedicine2018
Retrospective analysis of prognosis and risk factors of patients with stroke by TOAST.
Article in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Incidence of First-Ever Stroke, Stroke Events, and Early Case Fatality Rate in China: Results from a National Population-Based Survey.Neuroepidemiology · 2025Article
- Predictive value of neutrophil to apolipoprotein A1 ratio in patients with acute ischaemic stroke.Brain communications · 2024Article
- Machine learning-based prediction of one-year mortality in ischemic stroke patients.Oxford open neuroscience · 2024Article
- Undiagnosed major risk factors in acute ischaemic stroke patients in Qatar: analysis from the Qatar stroke registry.BMJ neurology open · 2024Article
- Association between atherosclerosis and the development of multi-organ pathologies.SAGE open medicine · 2024Review
- Predicting 90-Day Prognosis in Ischemic Stroke Patients Post Thrombolysis Using Machine Learning.Journal of personalized medicine · 2023Article
- [The Occurrence and Risk Factors of Stroke Complicated by Venous Thromboembolism].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2023Article
- Abnormal expression of miRNA-122 in cerebral infarction and related mechanism of regulating vascular endothelial cell proliferation and apoptosis by targeting CCNG1.Clinics (Sao Paulo, Brazil) · 2023Article
- Immune-inflammatory, coagulation, adhesion, and imaging biomarkers combined in machine learning models improve the prediction of death 1 year after ischemic stroke.Clinical and experimental medicine · 2022Article
- Carotid intima media thickness measurements coupled with stroke severity strongly predict short-term outcome in patients with acute ischemic stroke: a machine learning study.Metabolic brain disease · 2021Article
- Large disparities in 28-day case fatality by stroke subtype: data from a French stroke registry between 2008 and 2017.European journal of neurology · 2021Article
- In-hospital prognosis of first-ever noncardiogenic ischemic stroke in patients with and without indication for prestroke antiplatelet therapy: Chinese Stroke Center Alliance.Annals of translational medicine · 2021Article
- Outcomes of Ischemic Stroke and Associated Factors Among Elderly Patients With Large-Artery Atherosclerosis: A Hospital-Based Follow-Up Study in China.Frontiers in neurology · 2021Article
- Article
- Clinical outcomes of cerebral infarction in nonagenarians compared among four age groups.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020Article
- Lifestyles correlate with stroke recurrence in Chinese inpatients with first-ever acute ischemic stroke.Journal of neurology · 2019Article
- Observational
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7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To determine differences in 90-day mortality and identify risk factors among different etiological classifications of ischemic stroke using the Trial of ORG 10172 in Acute Stroke Treatment (TOAST) classification.Our retrospective analysis included 538 ischemic stroke patients. The cause of stroke was categorized according to the TOAST criteria, and 90-day mortality rates were obtained through the patient follow-up. Age, sex, previous medical history, and clinical features were used in the analysis of potential risk factors.There were 38 deaths during the 90-day follow-up period. Patients in the undetermined cause subgroups experienced significantly higher mortality rate than those in subgroups with small artery occlusion and large artery atherosclerosis. Factors independently associated with 90-day mortality for patients with the large artery atherosclerosis stroke subtype were age (95% confidence interval [CI], 1.010-1.192, P = .028), history of hypertension (95% CI, 3.030-99.136, P = .001), high blood glucose (95% CI, 1.273-2.354, P < .001), high cholesterol (95% CI, 0.017-0.462, P = .004), high uric acid (95% CI, 2.360-64.389, P = .003), and National Institute of Health Stroke Scale(95% CI, 1.076-1.312, P = .001). Age (95% CI, 1.012-1.358, P = .034) and high cholesterol (95% CI, 0.011-0.496, P = .007) were independently associated with 90-day mortality for patients with the small artery occlusion subtype of stroke.Our analysis identified that certain risk factors and 90-day mortality differ significantly among different stroke subtypes, as classified by the TOAST criteria. These risk factors must be considered carefully to provide the best clinical management of these patients and thus reduce mortality.
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