Trial reportMedicine2018
Extent of simultaneous radiation dose and iodine reduction at stable image quality in computed tomography of the chest: A systematic approach using automated tube voltage adaption and iterative reconstructions.
Trial report in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 5 citations in OpenAlex.
- Use of ultra-low contrast dose CT aortography for the management of aortic aneurysmal disease.Journal of cardiothoracic surgery · 2024Article
- Structured Digital Self-Assessment of Patient Anamnesis Prior to Computed Tomography: Performance Evaluation and Added Value.Journal of medical systems · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAim of this study was to systematically combine tube voltage adaptation and iterative reconstructions for reduction of iodine and radiation dose.
methodsSettings for the study protocol were evaluated in ex-ante trials to provide image quality that is comparable to a reference protocol at 120 kV with tube current modulation. Consecutive patients were randomized to undergo computed tomography (CT) of the chest using the study protocol (n = 62) or reference protocol (n = 50). Objective and subjective image quality was assessed and compared.
resultsTube voltage was decreased to 100 kV in 47 patients and to 80 kV in 15 patients in the study group. The iodine dosage (16.1 vs 10.5 g) and the effective radiation dose (3.6 vs 2.5 mSv) were significantly decreased in the study group (both P < .001). Contrast-to-noise ratio was comparable in the pulmonary trunk and increased in the aorta (P < .01). Subjective image quality was comparable without statistically significance.
conclusionsSimultaneous reductions in iodine dosage and radiation dose by one-third are feasible for CT of the chest.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.