Trial reportPsychosomatic medicine2018
Common and Dissociable Neural Activity After Mindfulness-Based Stress Reduction and Relaxation Response Programs.
Trial report in Psychosomatic medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05223348 (Examining the Role of Perceived Body Boundaries and Spatial Frame of Reference in the Mechanism of Action of a Body Scan Meditation in Reducing Emotional Eating), which is not on this map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Examining the Role of Perceived Body Boundaries and Spatial Frame of Reference in the Mechanism of Action of a Body Scan Meditation in Reducing Emotional Eating: A Randomized Controlled Study
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Mindfulness-based programmes for mental health promotion in adults in nonclinical settings: A systematic review and meta-analysis of randomised controlled trials.PLoS medicine · 2021Pooled it
- Virtual reality enhanced mindfulness and yoga intervention for postpartum depression and anxiety in the post COVID era.Scientific reports · 2025Trial
- "Practice Makes Perfect"? Associations Between Home Practice and Physical and Emotional Function Outcomes Among Patients with Chronic Pain Enrolled in a Mind-Body Program.Journal of integrative and complementary medicine · 2022Trial
- Participant experiences of change in mindfulness-based stress reduction for anxiety disorders.International journal of qualitative studies on health and well-being · 2020Trial
- Effects of attachment-based compassion therapy (ABCT) on brain-derived neurotrophic factor and low-grade inflammation among fibromyalgia patients: A randomized controlled trial.Scientific reports · 2019Trial
- Reducing compulsive Internet use and anxiety symptoms via two brief interventions: A comparison between mindfulness and gradual muscle relaxation.Journal of behavioral addictions · 2019Trial
- Distinct and shared therapeutic neural mechanisms of mindfulness-based and social support stress reduction groups in adults with autism spectrum disorder.Journal of psychiatry & neuroscience : JPNTrial
- A taxonomic framework of music-based intervention components to guide research: recommendations from the NIH U24 music research networks.Frontiers in psychology · 2026Article
- Study on the intervention effect of mindfulness-based stress reduction on postoperative cognitive dysfunction and psychological resilience in lung cancer patients.Frontiers in neurology · 2025Article
- Remodeling the Epigenome Through Meditation: Effects on Brain, Body, and Well-being.Sub-cellular biochemistry · 2025Review
- What can the psychoneuroimmunology of yoga teach us about depression's psychopathology?Brain, behavior, & immunity - health · 2024Article
- Barriers and Facilitators to Incorporating an Integrative Mind-Body Intervention in Youth With Type 2 Diabetes.JAACAP open · 2024Article
- A Female-Specific Treatment Group for ADHD-Description of the Programme and Qualitative Analysis of First Experiences.Journal of clinical medicine · 2024Article
- Mindfulness-based therapy improves brain functional network reconfiguration efficiency.Translational psychiatry · 2023Article
- Article
- Interoceptive awareness: MBSR training alters information processing of salience network.Frontiers in behavioral neuroscience · 2023Article
- Neurofeedback-Augmented Mindfulness Training Elicits Distinct Responses in the Subregions of the Insular Cortex in Healthy Adolescents.Brain sciences · 2022Article
- Integrative Body, Mind, and Spirit Interventions used with Parents in the Child Welfare System.Journal of child & adolescent trauma · 2022Article
- Enhanced Resting-State Functional Connectivity With Decreased Amplitude of Low-Frequency Fluctuations of the Salience Network in Mindfulness Novices.Frontiers in human neuroscience · 2022Article
- The role of mindfulness and relaxation in improved sleep quality following a mind-body and activity program for chronic pain.Mindfulness · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
objectiveWe investigated common and dissociable neural and psychological correlates of two widely used meditation-based stress reduction programs.
methodsParticipants were randomized to the Relaxation Response (RR; n = 18; 56% female) or the Mindfulness-Based Stress Reduction (MBSR; n = 16; 56% female) programs. Both programs use a "bodyscan" meditation; however, the RR program explicitly emphasizes physical relaxation during this practice, whereas the MBSR program emphasizes mindful awareness with no explicit relaxation instructions. After the programs, neural activity during the respective meditation was investigated using functional magnetic resonance imaging.
resultsBoth programs were associated with reduced stress (for RR, from 14.1 ± 6.6 to 11.3 ± 5.5 [Cohen's d = 0.50; for MBSR, from 17.7 ± 5.7 to 11.9 ± 5.0 [Cohen's d = 1.02]). Conjunction analyses revealed functional coupling between ventromedial prefrontal regions and supplementary motor areas (p < .001). The disjunction analysis indicated that the RR bodyscan was associated with stronger functional connectivity of the right inferior frontal gyrus-an important hub of intentional inhibition and control-with supplementary motor areas (p < .001, family-wise error [FWE] rate corrected). The MBSR program was uniquely associated with improvements in self-compassion and rumination, and the within-group analysis of MBSR bodyscan revealed significant functional connectivity of the right anterior insula-an important hub of sensory awareness and salience-with pregenual anterior cingulate during bodyscan meditation compared with rest (p = .03, FWE corrected).
conclusionsThe bodyscan exercises in each program were associated with both overlapping and differential functional coupling patterns, which were consistent with each program's theoretical foundation. These results may have implications for the differential effects of these programs for the treatment of diverse conditions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.