Evidence map›Paper›PMID 29642066›Full record

ReviewJournal of innate immunity2018

Neutrophils and Bacterial Immune Evasion.

Scott D Kobayashi, Natalia Malachowa, Frank R DeLeo

Registry-linked trialAbstract readReview
In one paragraph

Review in Journal of innate immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00339287 (Molecular Basis of Human Phagocyte Interactions With Bacterial Pathogens), which is not on this map. Cited by 133 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
133citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00339287 recruitingnot on this map

Molecular Basis of Human Phagocyte Interactions With Bacterial Pathogens

TypeobservationalSponsorNational Institute of Allergy and Infectious Diseases (NIAID)Ran2001Enrolled200ConditionsHost Defense Mechanisms
3 · Its place in the literature

Who cites it

133 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. The Relationship Between Severity of Apical Periodontitis and Next-Generation Systemic Inflammatory Biomarkers.Australian endodontic journal : the journal of the Australian Society of Endodontology Inc · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Infection and immunity · 2026
    Article
  10. Article
  11. Article
  12. Microbial and host innate immune factors affecting the persistence ofFrontiers in cellular and infection microbiology · 2026
    Review
  13. Article
  14. Review
  15. The applicability of the MigratestBMC veterinary research · 2025
    Article
  16. Article
  17. Review
  18. Article
  19. Infection and immunity · 2025
    Article
  20. Article

73 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Scott D Kobayashi
Natalia Malachowa
Frank R DeLeo

Funding

Interaction of pathogenic bacteria with human phagocytic leukocytesZIAAI000900 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI DELEO, FRANK · 2009 to 2023
$3.6M
6 · The paper itself

Abstract

Neutrophils are an important component of the innate immune system and provide a front line of defense against bacterial infection. Although most bacteria are killed readily by neutrophils, some bacterial pathogens have the capacity to circumvent destruction by these host leukocytes. The ability of bacterial pathogens to avoid killing by neutrophils often involves multiple attributes or characteristics, including the production of virulence molecules. These molecules are diverse in composition and function, and collectively have the potential to alter or inhibit neutrophil recruitment, phagocytosis, bactericidal activity, and/or apoptosis. Here, we review the ability of bacteria to target these processes.

Indexed as

AnimalsApoptosisBacterial InfectionsHumansImmune EvasionImmunity, InnateInflammationNeutrophil InfiltrationNeutrophilsVirulence FactorsVirulence FactorsBacterial pathogenesisHost defenseInnate immunityNeutrophilPhagocytosisVirulence

Identifiers

PMID29642066
PMCPMC6784029

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.