Evidence map›Paper›PMID 29642034›Full record

ArticleBiophysical journal2018

TnI Structural Interface with the N-Terminal Lobe of TnC as a Determinant of Cardiac Contractility.

Anthony D Vetter, Evelyne M Houang, Jordan J Sell, Brian R Thompson, Yuk Y Sham, Joseph M Metzger

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biophysical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. OR-1896 increases force of contraction in the isolated human atrium.Naunyn-Schmiedeberg's archives of pharmacology · 2023
    Article
  3. Article
  4. Article
  5. Article
  6. Computational Studies of Cardiac and Skeletal Troponin.Frontiers in molecular biosciences · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Anthony D VetterDepartment of Integrative Biology and Physiology, College of Medicine, University of Minnesota, Minneapolis, Minnesota.
Evelyne M HouangDepartment of Integrative Biology and Physiology, College of Medicine, University of Minnesota, Minneapolis, Minnesota.
Jordan J SellDepartment of Integrative Biology and Physiology, College of Medicine, University of Minnesota, Minneapolis, Minnesota.
Brian R ThompsonDepartment of Integrative Biology and Physiology, College of Medicine, University of Minnesota, Minneapolis, Minnesota.
Yuk Y ShamDepartment of Integrative Biology and Physiology, College of Medicine, University of Minnesota, Minneapolis, Minnesota.
Joseph M MetzgerDepartment of Integrative Biology and Physiology, College of Medicine, University of Minnesota, Minneapolis, Minnesota. Electronic address: metzgerj@umn.edu.
University of Minnesota · US

Funding

Myofilaments as regulators of heart function in diseaseR01HL132874 · NHLBI · UNIVERSITY OF MINNESOTA · PI METZGER, JOSEPH MARK · 2017 to 2025
$3.7M
NHLBI NIH HHS R01 HL132874
6 · The paper itself

Abstract

The heterotrimeric cardiac troponin complex is a key regulator of contraction and plays an essential role in conferring Ca

Indexed as

Myocardial ContractionAnimalsFemaleHEK293 CellsHumansMolecular Dynamics SimulationProtein BindingProtein Conformation, alpha-HelicalRatsRats, Sprague-DawleyTroponin CTroponin ITroponin CTroponin I

Identifiers

PMID29642034
PMCPMC5954295
OpenAlexW2797838544

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.