ArticleCell reports2018
Cardiomyocyte Membrane Structure and cAMP Compartmentation Produce Anatomical Variation in β
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Article in Cell reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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37citing papers in PubMed
6.5field-weighted citation impact, top 3% of its field
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Who cites it
37 citing papers in PubMed, 64 citations in OpenAlex.
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- Autonomic imbalance in cardiovascular disease: molecular mechanisms and emerging therapeutics.American journal of physiology. Cell physiology · 2025Review
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- Stretch regulation of β2-Adrenoceptor signalling in cardiomyocytes requires caveolae.Cardiovascular research · 2025Article
- Mortality risk stratification for Takotsubo syndrome: Evaluating CRP measurement alongside the InterTAK prognostic score.ESC heart failure · 2025Article
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- Perioperative management of Takotsubo cardiomyopathy: an overview.Journal of anesthesia, analgesia and critical care · 2024Review
- Modelling hemodynamics regulation in rats and dogs to facilitate drugs safety risk assessment.Frontiers in pharmacology · 2024Article
- Protective effect of UDCA against IL-11- induced cardiac fibrosis is mediated by TGR5 signalling.Frontiers in cardiovascular medicine · 2024Article
- Pulmonary Hypertension-Associated Right Ventricular Cardiomyocyte Remodelling Reduces Treprostinil Function.Cells · 2023Article
- Caveolae-associated cAMP/CaJournal of molecular and cellular cardiology · 2023Article
- Caveolin-3 and Caveolae regulate ventricular repolarization.Journal of molecular and cellular cardiology · 2023Article
- Whole-heart multiparametric optical imaging reveals sex-dependent heterogeneity in cAMP signaling and repolarization kinetics.Science advances · 2023Article
- Review
- Molecular Mechanisms of Takotsubo Syndrome.International journal of molecular sciences · 2022Review
- Circulating microRNAs predispose to takotsubo syndrome following high-dose adrenaline exposure.Cardiovascular research · 2022Article
- Phosphodiesterases and Compartmentation of cAMP and cGMP Signaling in Regulation of Cardiac Contractility in Normal and Failing Hearts.International journal of molecular sciences · 2022Review
- Takotsubo Syndrome: Translational Implications and Pathomechanisms.International journal of molecular sciences · 2022Review
Corrections and comments
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Authors and funding
17 authors at 8 institutions in 4 countries.
Peter T WrightMyocardial Function, National Heart and Lung Institute, Imperial College London, ICTEM, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK.
Navneet K BhogalMyocardial Function, National Heart and Lung Institute, Imperial College London, ICTEM, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK.
Ivan DiakonovMyocardial Function, National Heart and Lung Institute, Imperial College London, ICTEM, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK.
Laura M K PannellMyocardial Function, National Heart and Lung Institute, Imperial College London, ICTEM, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK.
Ruwan K PereraInstitute of Experimental Cardiovascular Research, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Nadja I BorkInstitute of Experimental Cardiovascular Research, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Sophie SchobesbergerMyocardial Function, National Heart and Lung Institute, Imperial College London, ICTEM, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK; Institute of Experimental Cardiovascular Research, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Carla LucarelliMyocardial Function, National Heart and Lung Institute, Imperial College London, ICTEM, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK; Department of Cardiac Surgery, University of Verona School of Medicine, Azienda Ospedalieria Universitaria Integrata, Borgo Trento Piazzale A. Stefani, 37126 Verona, Italy.
Giuseppe FaggianDepartment of Cardiac Surgery, University of Verona School of Medicine, Azienda Ospedalieria Universitaria Integrata, Borgo Trento Piazzale A. Stefani, 37126 Verona, Italy.
Anita Alvarez-LaviadaMyocardial Function, National Heart and Lung Institute, Imperial College London, ICTEM, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK.
Manuela ZaccoloDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3QX, UK.
Timothy J KampDepartment of Medicine, University of Wisconsin Madison, 1111 Highland Ave., Madison, WI 53705-2275, USA.
Ravi C BalijepalliDepartment of Medicine, University of Wisconsin Madison, 1111 Highland Ave., Madison, WI 53705-2275, USA.
Alexander R LyonMyocardial Function, National Heart and Lung Institute, Imperial College London, ICTEM, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK; NIHR Cardiovascular Biomedical Research Unit, Royal Brompton Hospital, London SW7 3AZ, UK.
Sian E HardingMyocardial Function, National Heart and Lung Institute, Imperial College London, ICTEM, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK.
Viacheslav O NikolaevInstitute of Experimental Cardiovascular Research, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Julia GorelikMyocardial Function, National Heart and Lung Institute, Imperial College London, ICTEM, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK. Electronic address: j.gorelik@imperial.ac.uk.
Hammersmith Hospital · GBUniversity Medical Center Hamburg-Eppendorf · DEUniversity of Wisconsin–Madison · USAzienda Ospedaliera Universitaria Integrata Verona · ITImperial College London · GBUniversität Hamburg · DEUniversity of Oxford · GBUniversity of Verona · IT
Funding
The Virtual Physiological Rat ProjectP50GM094503 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BEARD, DANIEL A · 2011 to 2015
$11.6MCaveolae and L-type Calcium Channels in CardiomyocytesR01HL078878 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI BALIJEPALLI, RAVI CHANDRA, KAMP, TIMOTHY J. · 2007 to 2016
$3.1MBritish Heart Foundation FS/11/67/28954British Heart Foundation JG12/18/30088British Heart Foundation PG/15/5/31110British Heart Foundation RG/12/3/29423British Heart Foundation RG/17/13/33173Medical Research Council MR/L006855/1NHLBI NIH HHS R01 HL078878NIGMS NIH HHS P50 GM094503
Abstract
Cardiomyocytes from the apex but not the base of the heart increase their contractility in response to β
Indexed as
Adrenergic beta-2 Receptor AgonistsAnimalsbeta-CyclodextrinsCaveolin 3Cell MembraneCholesterolCyclic AMPCyclic Nucleotide Phosphodiesterases, Type 4FemaleHeartIsoproterenolMaleMiceMice, KnockoutMuscle ContractionMyocytes, CardiacAdrenergic beta-2 Receptor Agonistsbeta-CyclodextrinsCav3 protein, mouseCaveolin 3CholesterolCyclic AMPCyclic Nucleotide Phosphodiesterases, Type 4Isoproterenolmethyl-beta-cyclodextrinReceptors, Adrenergic, beta-2cAMPcardiomyocytescaveolaemicrodomainsT-tubulesβ(2) adrenoceptor
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.