Evidence map›Paper›PMID 29641907›Full record

ReviewAnnual review of biomedical engineering2018

Physiology and Engineering of the Graded Interfaces of Musculoskeletal Junctions.

Edward D Bonnevie, Robert L Mauck

Abstract readReview
In one paragraph

Review in Annual review of biomedical engineering, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Hydrogel Development for Rotator Cuff Repair.Frontiers in bioengineering and biotechnology · 2022
    Review
  13. Article
  14. [Research progress of interfacial tissue engineering in rotator cuff repair].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2021
    Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Edward D BonnevieMcKay Orthopaedic Research Laboratory, Department of Orthopaedic Surgery, and Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA; email: lemauck@mail.med.upenn.edu.
Robert L MauckMcKay Orthopaedic Research Laboratory, Department of Orthopaedic Surgery, and Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA; email: lemauck@mail.med.upenn.edu.

Funding

Overall: Resource-based Center for Musculoskeletal Disorders Research (Overall Application)P30AR069619 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI LOUIS J SOSLOWSKY · 2016 to 2026
$9.1M
The Role of Hyaluronic Acid Receptors in Tendon HealingP30AR050950 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI PIGNOLO, ROBERT JOHN · 2006 to 2015
$6.2M
Training in Muscle Biology and Muscle DiseaseT32AR053461 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI OSTAP, E. MICHAEL · 2006 to 2025
$4.9M
Multi-scale biomechanics of engineered and native fibrous load-bearing tissueR01EB002425 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI ELLIOTT, DAWN M, MAUCK, ROBERT L · 2003 to 2017
$4.1M
NIAMS NIH HHS P30 AR050950NIAMS NIH HHS P30 AR069619NIAMS NIH HHS T32 AR053461NIBIB NIH HHS R01 EB002425RRD VA I01 RX002274
6 · The paper itself

Abstract

The connective tissues of the musculoskeletal system can be grouped into fibrous, cartilaginous, and calcified tissues. While each tissue type has a distinct composition and function, the intersections between these tissues result in the formation of complex, composite, and graded junctions. The complexity of these interfaces is a critical aspect of their healthy function, but poses a significant challenge for their repair. In this review, we describe the organization and structure of complex musculoskeletal interfaces, identify emerging technologies for engineering such structures, and outline the requirements for assessing the complex nature of these tissues in the context of recapitulating their function through tissue engineering.

Indexed as

Tissue ScaffoldsAnimalsBone and BonesCartilage, ArticularHumansIntervertebral DiscLigamentsTemporomandibular JointTendonsTissue Engineeringarticular cartilagebonegradientsinterfacesintervertebral disctemporomandibular jointtendon

Identifiers

PMID29641907
PMCPMC7735380

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.