ReviewAnais brasileiros de dermatologia
Erythromelalgia: a cutaneous manifestation of neuropathy?
Review in Anais brasileiros de dermatologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- Small Fiber Neuropathy in Burning Mouth Syndrome: A Systematic Review.International journal of molecular sciences · 2024Pooled it
- Erythromelalgia mimicking diabetic foot infection: diagnostic challenges and contraindication of ice application.Journal of medical case reports · 2026Article
- Acrocyanosis: The Least Known Acrosyndrome Revisited With a Dermatologic Perspective.Dermatology research and practice · 2025Review
- Mepyramine targets mutant Nav1.7 channels to relieve pain and erythema in primary erythromelalgia patients.Frontiers in medicine · 2025Article
- Mimicking the Usual Suspects: Erythromelalgia in the Differential Diagnosis.Journal of Brown hospital medicine · 2025Article
- Intravenous immunoglobulin therapy in erythromelalgia management: a case report.Einstein (Sao Paulo, Brazil) · 2025Article
- Hyper-dilute botulinum toxin as an effective treatment for refractory erythromelalgia.JAAD case reports · 2024Article
- Studying Erythromelalgia Using Doppler Flowmetry Perfusion Signals and Wavelet Analysis-An Exploratory Study.Biomedicines · 2023Article
- Part II: Cutaneous manifestations of peripheral vascular disease.Journal of the American Academy of Dermatology · 2023Review
- Erythromelalgia in a patient with feet erythema and cyanosis.BMJ case reports · 2023Article
- Endoscopic lumbar sympathectomy as a treatment option for primary erythromelalgia - case report and review.Jornal vascular brasileiro · 2023Article
- A case of erythromelalgia with gastrointestinal dysautonomia treated with immunoglobulin: A case report.SAGE open medical case reports · 2023Article
- Erythromelalgia Associated with Neuropathy in Sjögren's Syndrome: A Case Report.Acta dermato-venereologica · 2022Article
- Auricular erythermalgia showing excellent response to itraconazole: a case report.Therapeutic advances in chronic disease · 2022Article
- Fish Oil and BCQ™ as a Novel Treatment Approach to Primary Erythromelalgia: A Case Study.Integrative medicine (Encinitas, Calif.) · 2021Article
- Painful, reappearing eruption in a medically complex 4-year-old.BMJ case reports · 2021Article
- A case of sporadic erythromelalgia presenting with small fibre neuropathy.BMJ case reports · 2019Article
- Vascular acrosyndromes in young adult population. Definition of clinical symptoms and connections to joint hypermobility.Clinical rheumatology · 2019Observational
- Cyclosporine-induced Erythromelalgia.Cureus · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The low prevalence of erythromelalgia, classified as an orphan disease, poses diagnostic and therapeutic difficulties. The aim of this review is to be an update of the specialized bibliography. Erythromelalgia is an infrequent episodic acrosyndrome affecting mainly both lower limbs symmetrically with the classic triad of erythema, warmth and burning pain. Primary erythromelalgia is an autosomal dominant inherited disorder, while secondary is associated with myeloproliferative diseases, among others. In its etiopathogenesis, there are neural and vascular abnormalities that can be combined. The diagnosis is based on exhaustive clinical history and physical examination. Complications are due to changes in the skin barrier function, ischemia and compromise of cutaneous nerves. Because of the complexity of its pathogenesis, erythromelalgia should always be included in the differential diagnosis of conditions that cause chronic pain and/or peripheral edema. The prevention of crisis is based on a strict control of triggers and promotion of preventive measures. Since there is no specific and effective treatment, control should focus on the underlying disease. However, there are numerous topical and systemic therapies that patients can benefit from.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.