Evidence map›Paper›PMID 29641454›Full record

ReviewFoods (Basel, Switzerland)2018

The Potential Health Benefits of Noni Juice: A Review of Human Intervention Studies.

Brett J West, Shixin Deng, Fumiyuki Isami, Akemi Uwaya, Claude Jarakae Jensen

Open access · goldAbstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
9.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 73 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Research progress on microRNA in gout.Frontiers in pharmacology · 2022
    Review
  10. Article
  11. Article
  12. Review
  13. Acclimation potential of Noni (Plant signaling & behavior · 2021
    Article
  14. Secoiridoids and Iridoids fromJournal of natural products · 2020
    Article
  15. FermentedNutrients · 2020
    Article
  16. Hiccups: You got to be kidney me!SAGE open medical case reports · 2020
    Article
  17. Article
  18. Review
  19. Differential Influence ofIn vivo (Athens, Greece)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Brett J WestResearch and Development, Morinda, Inc., 737 East 1180 South, American Fork, UT 84003, USA. brett_west@morinda.com.ORCID 0000-0003-0577-7532
Shixin DengResearch and Development, Morinda, Inc., 737 East 1180 South, American Fork, UT 84003, USA. shixin_deng@morinda.com.
Fumiyuki IsamiResearch and Development, Morinda, Inc., 3-2-2 Nishishinjuku, Shinjuku-ku, Tokyo 160-0023, Japan. fumiyuki_isami@jp.morinda.com.
Akemi UwayaResearch and Development, Morinda, Inc., 3-2-2 Nishishinjuku, Shinjuku-ku, Tokyo 160-0023, Japan. akemi_uwaya@jp.morinda.com.
Claude Jarakae JensenResearch and Development, Morinda, Inc., 737 East 1180 South, American Fork, UT 84003, USA. jarakae_jensen@morinda.com.
American Fork Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Noni juice is a globally popular health beverage originating in the tropics. Traditional Tahitian healers believe the noni plant to be useful for a wide range of maladies, and noni juice consumers throughout the world have similar perceptions. Nevertheless, human clinical trials are necessary for a precise understanding of what the health benefits of noni juice are. A review of published human intervention studies suggests that noni juice may provide protection against tobacco smoke-induced DNA damage, blood lipid and homocysteine elevation as well as systemic inflammation. Human intervention studies also indicate that noni juice may improve joint health, increase physical endurance, increase immune activity, inhibit glycation of proteins, aid weight management, help maintain bone health in women, help maintain normal blood pressure, and improve gum health. Further, these studies point to notable antioxidant activity in noni juice, more so than other fruit juices which served as trial placebos. It is this antioxidant effect and its interaction with the immune system and inflammation pathways that may account for many of the observed health benefits of noni juice. However, the existing evidence does have some limitations as far as its general application to noni juice products; all the peer-reviewed human interventions studies to date have involved only one source of French Polynesian noni juice. Geographical factors and variations in processing methods are known to produce commercial noni juice products with divergent phytochemical and nutrient compositions. Therefore, other sources of noni products may have different toxicological and pharmacological profiles.

Indexed as

antioxidantclinical trialimmune systeminflammationMorinda citrifolianoni juice

Identifiers

PMID29641454
PMCPMC5920423
OpenAlexW2790119072

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.