Evidence map›Paper›PMID 29637817›Full record

ArticleCell transplantation2018

Clinical Cell Therapy Guidelines for Neurorestoration (IANR/CANR 2017).

Hongyun Huang, Wise Young, Lin Chen, Shiqing Feng, Ziad M Al Zoubi, Hari Shanker Sharma, Hooshang Saberi, Gustavo A Moviglia, Xijing He, Dafin F Muresanu and 57 more

Abstract read
In one paragraph

Article in Cell transplantation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  19. Stem cell therapy in autism: recent insights.Stem cells and cloning : advances and applications · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

67 authors.

Hongyun Huang1 Institute of Neurorestoratology, General Hospital of Armed Police Forces, Beijing, People's Republic of China.
Wise Young2 W. M. Keck Center for Collaborative Neuroscience, Rutgers, State University of New Jersey, Piscataway, NJ, USA.
Lin Chen3 Department of Neurosurgery, Tsinghua University Yuquan Hospital, Beijing, People's Republic of China.
Shiqing Feng4 Department of Orthopaedics, Tianjin Medical University General Hospital, Tianjin, People's Republic of China.
Ziad M Al Zoubi5 Jordan Ortho and Spinal Centre, Al-Saif Medical Center, Amman, Jordan.
Hari Shanker Sharma6 Intensive Experimental CNS Injury and Repair, University Hospital, Uppsala University, Uppsala, Sweden.
Hooshang Saberi7 Department of Neurosurgery, Brain and Spinal Injury Research center, Tehran University of Medical Sciences, Tehran, Iran.
Gustavo A Moviglia8 Center of Research and Engineer of Tissues and Cellular Therapy, Maimonides University, Buenos Aires, Argentina.
Xijing He9 Department of Orthopaedics, Second Affiliated Hospital of Xi'an Jiaotong University, Xian, People's Republic of China.
Dafin F Muresanu10 Department of Neurosciences "Iuliu Hatieganu," University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Alok Sharma11 Department of Neurosurgery, LTM Medical College, LTMG Hospital, Mumbai, Mumbai, India.
Ali Otom12 Royal Rehabilitation Center, King Hussein Medical Centre-RJRC Amman, Jordan.
Russell J Andrews13 Nanotechnology & Smart Systems, NASA Ames Research Center, Silicon Valley, CA, USA.
Adeeb Al-Zoubi14 The University of Illinois College of Medicine in Peoria, Peoria, IL, USA.
Andrey S Bryukhovetskiy15 NeuroVita Clinic of Interventional and Restorative Neurology and Therapy, Kashirskoye shosse, Moscow, Russia.
Elena R Chernykh16 Lab of Cellular Immunotherapy, Institute of Fundamental and Clinical Immunology, Novosibirsk, Russia.
Krystyna Domańska-Janik17 Stem Cell Bioengineering Unit, Mossakowski Medical Research Centre, Warsaw, Poland.
Emad Jafar5 Jordan Ortho and Spinal Centre, Al-Saif Medical Center, Amman, Jordan.
W Eustace Johnson18 Stem Cells and Regenerative Biology, Faculty of Medicine Dentistry and Life Sciences, University of Chester, Chester, United Kingdom.
Ying Li19 Spinal Repair Unit, Department of Brain Repair and Rehabilitation, UCL Institute of Neurology, London, United Kingdom.
Daqing Li19 Spinal Repair Unit, Department of Brain Repair and Rehabilitation, UCL Institute of Neurology, London, United Kingdom.
Zuo Luan20 Department of Pediatrics, Navy General Hospital of PLA, Beijing, People's Republic of China.
Gengsheng Mao1 Institute of Neurorestoratology, General Hospital of Armed Police Forces, Beijing, People's Republic of China.
Ashok K Shetty21 Department of Molecular and Cellular Medicine, Institute for Regenerative Medicine, Texas A&M Health Science Center College of Medicine, College Station, TX, USA.
Dario Siniscalco22 Department of Experimental Medicine, University of Campania "Luigi Vanvitelli," Naples, Italy.
Stephen Skaper23 Department of Pharmaceutical and Pharmacological Sciences, University of Padua, Padua, Italy.
Tiansheng Sun24 Department of orthopedics, PLA Army General Hospital, Beijing, People's Republic of China.
Yunliang Wang25 Department of Neurology, 148th Hospital, Zibo, Shandong, People's Republic of China.
Lars Wiklund26 Unit of Neurology, Department of Pharmacology and Clinical Neuroscience, Umea University, Ostersund, Sweden.
Qun Xue27 Department of Neurology, the First Affiliated Hospital of Soochow University, Suzhou Jiangsu, People's Republic of China.
Si-Wei You28 Department of Ophthalmology, Xijing Hospital, Fourth Military Medical University, Xi'an, People's Republic of China.
Zuncheng Zheng29 Department of Rehabilitation Medicine, The Central Hospital of Taian, Taian, Shandong, People's Republic of China.
Milan R Dimitrijevic30 Baylor College of Medicine, Houston, TX, USA.
W S El Masri31 Spinal Injuries Unit, Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, United Kingdom.
Paul R Sanberg32 Center of Excellence for Aging & Brain Repair, Morsani College of Medicine, University of South Florida, Tampa, FL, USA.
Qunyuan Xu33 Institute of Neuroscience, Capital Medical University, Beijing, People's Republic of China.
Guoming Luan34 Department of Neurosurgery, Beijing Sanbo Brain Hospital, Capital Medical University, Beijing, People's Republic of China.
Michael Chopp35 Henry Ford Hospital, Henry Ford Health System, Neurology Research, Detroit, MI, USA.
Kyoung-Suok Cho36 Department of Neurosurgery, Uijongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Uijongbu, South Korea.
Xin-Fu Zhou37 Division of Health Sciences, School of Pharmacy and Medical Sciences, Sansom Institute for Health Research, University of South Australia, Adelaide, South Australia, Australia.
Ping Wu38 Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, TX, USA.
Kai Liu39 Division of Life Science, The Hong Kong University of Science and Technology, Kowloon, Hong Kong.
Hamid Mobasheri40 Biomaterials Research Center, Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran.
Seiji Ohtori41 Department of Orthopedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Hiroyuki Tanaka42 Department of Orthopaedic Surgery, Graduate School of Medicine, Osaka University, Osaka, Japan.
Fabin Han43 Centre for Stem Cells and Regenerative Medicine, Liaocheng University/Liaocheng People's Hospital, Liaocheng, Shandong, People's Republic of China.
Yaping Feng44 Department of Neurosurgery, Kunming General Hospital of Chengdu Military Command of Chinese PLA, Kunming, Yunnan, People's Republic of China.
Shaocheng Zhang45 Department of Orthopedics, Changhai Hospital, The Second Military Medical University, Shanghai, People's Republic of China.
Yingjie Lu46 Department of Neurosurgery, Chengde Dadu Hospital, Weichang, Hebei, People's Republic of China.
Zhicheng Zhang24 Department of orthopedics, PLA Army General Hospital, Beijing, People's Republic of China.
Yaojian Rao47 Department of Spinal Surgery, Luoyang Orthopedic Hospital of Henan Province, Luoyang, Henan, People's Republic of China.
Zhouping Tang48 Department of Neurology, Tongji Medical College of HUST, Tongji Hospital, Wuhan, People's Republic of China.
Haitao Xi49 Department of Neurology, Beijing Rehabilitation Hospital of Capital Medical University, Beijing, People's Republic of China.
Liang Wu50 Center of Rehabilitation, Beijing Xiaotangshan Rehabilitation Hospital, Beijing, People's Republic of China.
Shunji Shen51 Department of Rehabilitation, Weihai Municipal Hospital, Weihai, Shandong, People's Republic of China.
Mengzhou Xue52 Department of Neurorehabilitation, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, People's Republic of China.
Guanghong Xiang53 Brain Hospital of Hunan Province, Changsha, Hunan, People's Republic of China.
Xiaoling Guo54 Department of Neurology, PLA Army 266 Hospital, Chengde, Hebei, People's Republic of China.
Xiaofeng Yang55 Department of Neurosurgery, The First Affiliated Hospital of Zhejiang University Medical College, Hangzhou, Zhejiang, People's Republic of China.
Yujun Hao56 Department of Neurosurgery, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, People's Republic of China.
Yong Hu57 Department of Orthopaedic and Traumatology, The University of Hong Kong, Pokfulam, Hong Kong.
Jinfeng Li26 Unit of Neurology, Department of Pharmacology and Clinical Neuroscience, Umea University, Ostersund, Sweden.
Qiang Ao58 Department of tissue engineering, China Medical University, Shenyang, Liaoning, People's Republic of China.
Bin Wang59 Department of Traumatology, The Second Affiliated Hospital of Guangzhou Medical University, Haizhu District, Guangzhou, People's Republic of China.
Zhiwen Zhang60 Department of Neurosurgery, First Affiliated Hospital of Chinese PLA General Hospital, Beijing, People's Republic of China.
Ming Lu61 Department of Neurosurgery, Second Affiliated Hospital of Hunan Normal University (163 Hospital of PLA), Changsha, Hunan, People's Republic of China.
Tong Li62 Department of Neurology, The Second Affiliated Hospital of Xinxiang Medical University, Xinxiang, Henan, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell therapy has been shown to be a key clinical therapeutic option for central nervous system diseases or damage. Standardization of clinical cell therapy procedures is an important task for professional associations devoted to cell therapy. The Chinese Branch of the International Association of Neurorestoratology (IANR) completed the first set of guidelines governing the clinical application of neurorestoration in 2011. The IANR and the Chinese Association of Neurorestoratology (CANR) collaborated to propose the current version "Clinical Cell Therapy Guidelines for Neurorestoration (IANR/CANR 2017)". The IANR council board members and CANR committee members approved this proposal on September 1, 2016, and recommend it to clinical practitioners of cellular therapy. These guidelines include items of cell type nomenclature, cell quality control, minimal suggested cell doses, patient-informed consent, indications for undergoing cell therapy, contraindications for undergoing cell therapy, documentation of procedure and therapy, safety evaluation, efficacy evaluation, policy of repeated treatments, do not charge patients for unproven therapies, basic principles of cell therapy, and publishing responsibility.

Indexed as

Cell- and Tissue-Based TherapyHumansNerve RegenerationQuality Controlcell therapyclinical application guideline neurorestoratologyneurorestoration

Identifiers

PMID29637817
PMCPMC5898693

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.