Evidence map›Paper›PMID 29637793›Full record

ReviewCritical reviews in biochemistry and molecular biology2018

Functions of the sirtuin deacylase SIRT5 in normal physiology and pathobiology.

Surinder Kumar, David B Lombard

Open access · greenAbstract readReview
In one paragraph

Review in Critical reviews in biochemistry and molecular biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 141 papers.

0numbers the graph read from it
0cells of the map it votes in
141citing papers in PubMed
11.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

141 citing papers in PubMed, 271 citations in OpenAlex.

  1. Trial
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  15. Biomarkers of Cardiac Metabolic Flexibility in Health, HFrEF and HFpEF.International journal of molecular sciences · 2026
    Review
  16. Article
  17. [Role of succinylation modification in central nervous system diseases].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Review
  18. Multi-omics reveals that genes linked to succinylation regulate the onset of epilepsy through metabolic reprogramming.Mammalian genome : official journal of the International Mammalian Genome Society · 2025
    Article
  19. Review
  20. Article

81 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Surinder Kumara Department of Pathology , University of Michigan , Ann Arbor , MI , USA.
David B Lombarda Department of Pathology , University of Michigan , Ann Arbor , MI , USA.
University of Michigan–Ann Arbor · US

Funding

Autophagy regulation of RSV-induced pulmonary diseaseR01HL114858 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LOMBARD, DAVID BENNER, LUKACS, NICHOLAS W · 2012 to 2019
$3.2M
Regulation of one carbon metabolism and epigenetics by SIRT5R01GM101171 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LOMBARD, DAVID BENNER · 2012 to 2021
$2.6M
Mechanisms of age-associated cardiac heterochromatin dysfunctionR21AG053561 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LOMBARD, DAVID BENNER · 2016 to 2016
$155k
NHLBI NIH HHS R01 HL114858NIA NIH HHS R21 AG053561NIGMS NIH HHS R01 GM101171
6 · The paper itself

Abstract

Sirtuins are NAD

Indexed as

AnimalsCitric Acid CycleFatty AcidsGlycolysisHumansMitochondrial ProteinsMyocardiumNeoplasmsNeurodegenerative DiseasesOncogene ProteinsReactive Oxygen SpeciesSirtuinsTumor Suppressor ProteinsFatty AcidsMitochondrial ProteinsOncogene ProteinsReactive Oxygen SpeciesSIRT5 protein, humanSirtuinsTumor Suppressor ProteinsglutarylationinhibitorsmalonylationmitochondriaSuccinylation

Identifiers

PMID29637793
PMCPMC6233320
OpenAlexW2799579025

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.