Evidence map›Paper›PMID 29637486›Full record

ArticleInternational journal of computer assisted radiology and surgery2018

A photon recycling approach to the denoising of ultra-low dose X-ray sequences.

Sai Gokul Hariharan, Norbert Strobel, Christian Kaethner, Markus Kowarschik, Stefanie Demirci, Shadi Albarqouni, Rebecca Fahrig, Nassir Navab

Abstract read
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In one paragraph

Article in International journal of computer assisted radiology and surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. An analytical approach for the simulation of realistic low-dose fluoroscopic images.International journal of computer assisted radiology and surgery · 2019
    Article
  4. Robust navigation support in lowest dose image setting.International journal of computer assisted radiology and surgery · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sai Gokul HariharanComputer Aided Medical Procedures, Technische Universität München, Munich, Germany. saigokul.hariharan@tum.de.ORCID http://orcid.org/0000-0002-4446-6799
Norbert StrobelSiemens Healthcare GmbH, Advanced Therapies, Forchheim, Germany.
Christian KaethnerSiemens Healthcare GmbH, Advanced Therapies, Forchheim, Germany.
Markus KowarschikComputer Aided Medical Procedures, Technische Universität München, Munich, Germany.
Stefanie DemirciComputer Aided Medical Procedures, Technische Universität München, Munich, Germany.
Shadi AlbarqouniComputer Aided Medical Procedures, Technische Universität München, Munich, Germany.
Rebecca FahrigSiemens Healthcare GmbH, Advanced Therapies, Forchheim, Germany.
Nassir NavabComputer Aided Medical Procedures, Technische Universität München, Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeClinical procedures that make use of fluoroscopy may expose patients as well as the clinical staff (throughout their career) to non-negligible doses of radiation. The potential consequences of such exposures fall under two categories, namely stochastic (mostly cancer) and deterministic risks (skin injury). According to the "as low as reasonably achievable" principle, the radiation dose can be lowered only if the necessary image quality can be maintained.

methodsOur work improves upon the existing patch-based denoising algorithms by utilizing a more sophisticated noise model to exploit non-local self-similarity better and this in turn improves the performance of low-rank approximation. The novelty of the proposed approach lies in its properly designed and parameterized noise model and the elimination of initial estimates. This reduces the computational cost significantly.

resultsThe algorithm has been evaluated on 500 clinical images (7 patients, 20 sequences, 3 clinical sites), taken at ultra-low dose levels, i.e. 50% of the standard low dose level, during electrophysiology procedures. An average improvement in the contrast-to-noise ratio (CNR) by a factor of around 3.5 has been found. This is associated with an image quality achieved at around 12 (square of 3.5) times the ultra-low dose level. Qualitative evaluation by X-ray image quality experts suggests that the method produces denoised images that comply with the required image quality criteria.

conclusionThe results are consistent with the number of patches used, and they demonstrate that it is possible to use motion estimation techniques and "recycle" photons from previous frames to improve the image quality of the current frame. Our results are comparable in terms of CNR to Video Block Matching 3D-a state-of-the-art denoising method. But qualitative analysis by experts confirms that the denoised ultra-low dose X-ray images obtained using our method are more realistic with respect to appearance.

Indexed as

AlgorithmsPhantoms, ImagingHumansPhotonsRadiation DosageRadiographySignal-To-Noise RatioSurgery, Computer-AssistedX-RaysLow-rank approximationSpatio-temporal denoisingUltra-low dose X-ray sequences

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.