Evidence map›Paper›PMID 29637399›Full record

ArticleIrish journal of medical science2019

Identifying risk factors associated with acquiring measles in an outbreak among age-appropriately vaccinated school children: a cohort analysis.

Bernadette O'Connor, Sarah Doyle

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In one paragraph

Article in Irish journal of medical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Vaccines for measles, mumps, rubella, and varicella in children.The Cochrane database of systematic reviews · 2021
    Pooled it
  3. Vaccines for measles, mumps, rubella, and varicella in children.The Cochrane database of systematic reviews · 2020
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Bernadette O'ConnorDepartment of Public Health, Health Service Executive South East, Lacken, Dublin Road, Kilkenny, R95 P231, Ireland.ORCID http://orcid.org/0000-0002-6863-4304
Sarah DoyleDepartment of Public Health, Health Service Executive South East, Lacken, Dublin Road, Kilkenny, R95 P231, Ireland. sarahm.doyle@hse.ie.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA measles outbreak occurred in age-appropriately vaccinated children in a school in a town in the South East of Ireland in September-November 2013.

aimsThe purpose of this study was to investigate the risk factors associated with catching measles during the outbreak.

methodsNinety-five children (4-5 years) in three classes, in the first year of primary school, were included in the study. Immunisation records on the South East Child Health Information System for first Measles Mumps and Rubella (MMR) vaccine for the 95 children were reviewed. Data collected included age at MMR, date of administration of MMR, MMR brand and batch number, and the General Practice at which MMR was administered. The risk factors analysed included age at vaccination, time of vaccination, class and the GP practice where MMR was administered. Statistical analysis was performed using Epi info 7 and SPSS v24.

resultsThirteen children in the cohort developed measles during the outbreak. All children in the cohort were age-appropriately vaccinated, with one dose of MMR vaccine. Analysis demonstrated statistically significant differences in the relative risk of developing measles according to the class a child was in, and the General Practice at which they were vaccinated.

conclusionsThe reason for intense measles activity in one class was not established. Although a concurrent investigation into cold chain and vaccine stock management did not identify a cause for the high relative risk of measles in children vaccinated, recommendations were made for improving cold chain and vaccine stock management in General Practices.

Indexed as

Disease OutbreaksVaccinationChild, PreschoolCohort StudiesFemaleHumansIrelandMaleMeaslesMeasles-Mumps-Rubella VaccineRisk FactorsMeasles-Mumps-Rubella VaccineCohortMeaslesOutbreakVaccination

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.