Evidence map›Paper›PMID 29637386›Full record

ArticleAIDS and behavior2018

Discordance of Self-report and Laboratory Measures of HIV Viral Load Among Young Men Who Have Sex with Men and Transgender Women in Chicago: Implications for Epidemiology, Care, and Prevention.

Brian Mustanski, Daniel T Ryan, Thomas A Remble, Richard T D'Aquila, Michael E Newcomb, Ethan Morgan

Open access · greenAbstract read
In one paragraph

Article in AIDS and behavior, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 26 citations in OpenAlex.

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  13. Transmission Risk Among Youth Living With HIV in the U.S.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Brian MustanskiInstitute for Sexual and Gender Minority Health and Wellbeing, Northwestern University, Chicago, IL, USA. brian@northwestern.edu.ORCID http://orcid.org/0000-0001-9222-5116
Daniel T RyanInstitute for Sexual and Gender Minority Health and Wellbeing, Northwestern University, Chicago, IL, USA.
Thomas A RembleInstitute for Sexual and Gender Minority Health and Wellbeing, Northwestern University, Chicago, IL, USA.
Richard T D'AquilaThird Coast Center for AIDS Research, Northwestern University, Chicago, IL, USA.
Michael E NewcombInstitute for Sexual and Gender Minority Health and Wellbeing, Northwestern University, Chicago, IL, USA.
Ethan MorganInstitute for Sexual and Gender Minority Health and Wellbeing, Northwestern University, Chicago, IL, USA.
Northwestern University · US

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Virology and Immunology Technology CoreP30AI117943 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Michael E Newcomb · 2015 to 2026
$38.4M
The RADAR cohort study of multilevel Influences on HIV and substance useU01DA036939 · NIDA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Brian Mustanski, Michael E Newcomb · 2014 to 2026
$29.5M
NCATS NIH HHS UL1 TR001422NIAID NIH HHS P30 AI117943NIDA NIH HHS U01 DA036939NIDA NIH HHS U01DA036939
6 · The paper itself

Abstract

Suppressing HIV viral load through daily antiretroviral therapy (ART) substantially reduces the risk of HIV transmission, however, the potential population impact of treatment as prevention (TasP) is mitigated due to challenges with sustained care engagement and ART adherence. For an undetectable viral load (VL) to inform decision making about transmission risk, individuals must be able to accurately classify their VL as detectable or undetectable. Participants were 205 HIV-infected young men who have sex with men (YMSM) and transgender women (TGW) from a large cohort study in the Chicago area. Analyses examined correspondence among self-reported undetectable VL, study-specific VL, and most recent medical record VL. Among HIV-positive YMSM/TGW, 54% had an undetectable VL (< 200 copies/mL) via study-specific laboratory testing. Concordance between self-report and medical record VL values was 80% and between self-report and study-specific laboratory testing was 73%; 34% of participants with a detectable study-specific VL self-reported an undetectable VL at last medical visit, and another 28% reported not knowing their VL status. Periods of lapsed viral suppression between medical visits may represent a particular risk for the TasP strategy among YMSM/TGW. Strategies for frequent viral load monitoring, that are not burdensome to patients, may be necessary to optimize TasP.

Indexed as

Self ReportSexual and Gender MinoritiesViral LoadAdultAnti-Retroviral AgentsBisexualityChicagoCohort StudiesCondomsFemaleHIV InfectionsHomosexuality, MaleHumansMaleSerologic TestsSexual BehaviorAnti-Retroviral AgentsMedical recordsTreatment as preventionUndetectableViral loadYoung MSM

Identifiers

PMID29637386
PMCPMC6721895
OpenAlexW2797093836

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.