Evidence map›Paper›PMID 29637165›Full record

ArticleBMJ paediatrics open2017

Assessing the quality of paediatric antibiotic prescribing by community paediatricians: a database analysis of prescribing in Lombardy.

Daniele Piovani, Antonio Clavenna, Massimo Cartabia, Angela Bortolotti, Ida Fortino, Luca Merlino, Maurizio Bonati

Open access · diamondAbstract read
In one paragraph

Article in BMJ paediatrics open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Daniele PiovaniDepartment of Public Health, Laboratory for Mother and Child Health, IRCCS - Istituto di Ricerche farmacologiche "Mario Negri", Milan, Italy.
Antonio ClavennaDepartment of Public Health, Laboratory for Mother and Child Health, IRCCS - Istituto di Ricerche farmacologiche "Mario Negri", Milan, Italy.
Massimo CartabiaDepartment of Public Health, Laboratory for Mother and Child Health, IRCCS - Istituto di Ricerche farmacologiche "Mario Negri", Milan, Italy.
Angela BortolottiRegional Health Ministry, Lombardy Region, Milan, Italy.
Ida FortinoRegional Health Ministry, Lombardy Region, Milan, Italy.
Luca MerlinoRegional Health Ministry, Lombardy Region, Milan, Italy.
Maurizio BonatiDepartment of Public Health, Laboratory for Mother and Child Health, IRCCS - Istituto di Ricerche farmacologiche "Mario Negri", Milan, Italy.
Mario Negri Institute for Pharmacological Research · ITRegione LombardiaIstituti di Ricovero e Cura a Carattere Scientifico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the quality of paediatricians' antibiotic prescribing using administrative databases.

methodsThe data source was the database of reimbursed prescriptions of the Lombardy Region, Italy. Children 1-13 years were included. An index prescription was defined as the first antibiotic prescription during a year period (2011) that occurred without previous, recent, antibiotic prescriptions or hospital or emergency department admissions. The A indicator was the percentage of children, cared for by paediatricians, receiving amoxicillin at the index prescription (minimum target 50%). The B indicator was the percentage of children receiving exclusively non-penicillin antibiotics in unrelated infection episodes (maximum target 10%). Indicators were evaluated for each prescriber and geographical area.

resultsOverall 424 280 children (cared for by 1164 paediatricians) received an index prescription and were included in the study. Amoxicillin alone was prescribed at the index prescription only to 23.6% of children (7.9%-46.3% within different areas of the region).The percentage of paediatricians who reached the target for the quality indicators was low (12.8% A indicator; 54.0% B indicator; 11.3% both). Almost half of the paediatricians (44.5%) showed inadequate quality of antibiotic prescribing, failing to reach the target for both indicators. Quality of prescribing was about four times worse in high prescribers and younger paediatricians. A geographical cluster of paediatricians reaching the target for both indicators was identified. These paediatricians had, for several years, previously been involved in educational programme.

conclusionsQuality of prescribing was generally unsatisfactory, but increased in a group of paediatricians previously involved in educational interventions and increased with increasing age. Further studies are warranted in order to validate these promising indicators as a benchmarking tool in other studies, when diagnosis is unknown.

Indexed as

anti-bacterial agentschildpaediatricianspharmacoepidemiologyquality of health care

Identifiers

PMID29637165
PMCPMC5862157
OpenAlexW2754697668

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.