Evidence map›Paper›PMID 29637157›Full record

ArticleBMJ paediatrics open2017

Influence of health insurance status on paediatric non-Hodgkin's lymphoma treatment in Kenya.

Hugo A Martijn, Festus Njuguna, Gilbert Olbara, Sandra Langat, Jodi Skiles, Stephen Martin, Terry Vik, Peter M van de Ven, Gertjan Jl Kaspers, Saskia Mostert

Abstract read
In one paragraph

Article in BMJ paediatrics open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Childhood Cancer Awareness Program in Bungoma County, Kenya.Journal of cancer education : the official journal of the American Association for Cancer Education · 2025
    Article
  6. Article
  7. Influence of health-insurance on treatment outcome of childhood cancer in Western Kenya.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
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  15. Article
  16. Patterns, treatments, and outcomes of pediatric central nervous system tumors in Sudan: a single institution experience.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hugo A MartijnDepartment of Pediatric Oncology-Hematology, VU University Medical Center, Amsterdam, The Netherlands.
Festus NjugunaDepartment of Child Health and Pediatrics, Moi Teaching and Referral Hospital, Eldoret, Kenya.
Gilbert OlbaraDepartment of Child Health and Pediatrics, Moi Teaching and Referral Hospital, Eldoret, Kenya.
Sandra LangatDepartment of Child Health and Pediatrics, Moi Teaching and Referral Hospital, Eldoret, Kenya.
Jodi SkilesDepartment of Pediatrics, Division of Hemato-Oncology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Stephen MartinDepartment of Pediatrics, Division of Hemato-Oncology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Terry VikDepartment of Pediatrics, Division of Hemato-Oncology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Peter M van de VenDepartment of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands.
Gertjan Jl KaspersDepartment of Pediatric Oncology-Hematology, VU University Medical Center, Amsterdam, The Netherlands.
Saskia MostertDepartment of Pediatric Oncology-Hematology, VU University Medical Center, Amsterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveNon-Hodgkin's lymphoma (NHL) is the most common childhood malignancy in sub-Saharan Africa. Survival rates for NHL are higher than 80% in high-income countries.This study explores treatment outcomes of children with NHL in Kenya, a sub-Saharan low-income country, and the association between health insurance status at diagnosis and treatment outcomes.

designThis was a retrospective medical records study. All children diagnosed with NHL in 2010, 2011 and 2012 were included. Data on treatment outcomes and health insurance status at diagnosis were collected.

resultsOf all 63 patients with NHL, 35% abandoned treatment, 22% had progressive or relapsed disease, 14% died and 29% had event-free survival. Most patients (73%) had no health insurance at diagnosis. Treatment outcomes in children with or without health insurance at diagnosis differed significantly (p=0.005). The most likely treatment outcome in children with health insurance at diagnosis was event-free survival (53%), whereas in children without health insurance at diagnosis it was abandonment of treatment (44%). Crude HR for treatment failure was 3.1 (95% CI 1.41 to 6.60, p=0.005) for uninsured versus insured children. The event-free survival estimate was significantly higher in children with health insurance at diagnosis than in patients without health insurance at diagnosis (p=0.003). Stage of disease at diagnosis was identified as a confounder of this association (adjusted HR=2.4, 95% CI 0.95 to 6.12, p=0.063).

conclusionsSurvival of children with NHL in Kenya is much lower compared with high-income countries. Abandonment of treatment is the most common cause of treatment failure. Health insurance at diagnosis was associated with better treatment outcomes and survival.

Indexed as

childhood cancerhealth insurance statuslow-income countrynon-Hodgkin's lymphoma

Identifiers

PMID29637157
PMCPMC5862191

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.