Evidence map›Paper›PMID 29637114›Full record

ArticleBMJ paediatrics open2017

Intrapartum intravenous fluids for caesarean delivery and newborn weight loss: a retrospective cohort study.

Sherif Eltonsy, Alain Blinn, Brigitte Sonier, Steven DeRoche, Aubin Mulaja, William Hynes, André Barrieau, Mathieu Belanger

Open access · diamondAbstract read
In one paragraph

Article in BMJ paediatrics open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Sherif EltonsyCentre de formation médicale du Nouveau-Brunswick, Moncton, Canada.
Alain BlinnDepartment of Family Medicine, Université de Sherbrooke, Sherbrooke, Canada.
Brigitte SonierResearch Centre, Vitalité Health Network, Moncton, Canada.
Steven DeRocheDepartment of Family Medicine, Université de Sherbrooke, Sherbrooke, Canada.
Aubin MulajaDepartment of Family Medicine, Université de Sherbrooke, Sherbrooke, Canada.
William HynesDepartment of Family Medicine, Université de Sherbrooke, Sherbrooke, Canada.
André BarrieauDepartment of Family Medicine, Université de Sherbrooke, Sherbrooke, Canada.
Mathieu BelangerCentre de formation médicale du Nouveau-Brunswick, Moncton, Canada.
Centre Médical de La Teppe · FRUniversité de Sherbrooke · CAVitalité Health Network · CACalifornia Maritime Academy · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo examine weight loss (WL) and excess weight loss (EWL) among newborns of caesarean delivery, comparing colloids plus crystalloids versus crystalloids only. Also, to examine different doses of intrapartum intravenous fluids on WL and EWL.

designComparative safety retrospective cohort study.

settingUniversity Teaching Hospital, Moncton, Canada. PATIENTS: Mothers exposed to intravenous fluids with caesarean delivery between 2008 and 2016.

interventionsExposure to colloids plus crystalloids was compared with crystalloids only, and dose-response analyses were performed for colloids, crystalloids and total intravenous fluids doses. Linear and logistic regression models were used, adjusting for potential confounders.

main outcome measuresInfants' WL was measured at days 1, 2 and 3 post partum, and EWL defined as loss of >7% of birth weight.

resultsFrom 801 mother-infant pairs, 176 were exposed to colloids plus crystalloids and 625 were exposed to crystalloids only (overall mean birth weight=3416 g, EWL=2%, 41.4% and 55.5% on days 1, 2 and 3, respectively). No significant difference in newborns' WL was observed on any of the days assessed. Adjusted OR (95% CI) of EWL was 1.0 (0.3 to 3.3) at 24 hours, 1.0 (0.7 to 1.5) at 48 hours and 1.4 (0.9 to 2.2) at 72 hours. No dose-response relationship was detected with type-specific and total intravenous fluids exposures.

conclusionsThe risk of EWL was similar with colloids plus crystalloids and crystalloids only, suggesting that both therapeutic options can be considered during caesarean delivery. The absence of dose-response relationships adds confirmatory evidence to the intravenous fluids safety profiles.

Indexed as

birth weightcaesarean sectioncolloidscrystalloidsweight loss

Identifiers

PMID29637114
PMCPMC5862158
OpenAlexW2742817981

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.