ArticleBMJ paediatrics open2017
Survey of nutritional practices during therapeutic hypothermia for hypoxic-ischaemic encephalopathy.
Article in BMJ paediatrics open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- A prospective study describing splanchnic NIRS and clinical outcomes in encephalopathic neonates receiving minimal enteral nutrition during therapeutic hypothermia.Journal of perinatology : official journal of the California Perinatal Association · 2025Trial
- Early versus delayed enteral nutrition for neonatal hypoxic-ischemic encephalopathy undergoing therapeutic hypothermia: a randomized controlled trial.Italian journal of pediatrics · 2022Trial
- Predictive model for feeding intolerance in neonates with hypoxic ischemic encephalopathy during therapeutic hypothermia.Scientific reports · 2025Article
- Minimal impact of feed intolerance during therapeutic hypothermia for hypoxic ischaemic encephalopathy in a South African cohort with a standardised feeding regimen.Frontiers in pediatrics · 2025Article
- Enteral Nutrition in Newborns with Hypoxic-Ischemic Encephalopathy Undergoing Therapeutic Hypothermia.Sisli Etfal Hastanesi tip bulteni · 2025Article
- Effects of Therapeutic Hypothermia and Minimal Enteral Nutrition on Short-Term Outcomes in Neonates with Hypoxic-Ischemic Encephalopathy: A 10-Year Experience from Oman.Children (Basel, Switzerland) · 2024Article
- Growth trajectories and need for oral feeding support among infants with neonatal encephalopathy treated with therapeutic hypothermia.Journal of perinatology : official journal of the California Perinatal Association · 2024Article
- Does enteral nutrition during therapeutic hypothermia increase the risk for necrotizing enterocolitis?Journal of perinatology : official journal of the California Perinatal Association · 2024Article
- Enteral nutritional strategy during therapeutic hypothermia: who? when? what?Frontiers in pediatrics · 2024Article
- Administration of parenteral nutrition during therapeutic hypothermia: a population level observational study using routinely collected data held in the National Neonatal Research Database.Archives of disease in childhood. Fetal and neonatal edition · 2021Observational
- Fluid Supply and Feeding Practices in Cooled Asphyxiated Newborns.Children (Basel, Switzerland) · 2021Article
- Nutritional management in newborn babies receiving therapeutic hypothermia: two retrospective observational studies using propensity score matching.Health technology assessment (Winchester, England) · 2021Article
- Feeding during neonatal therapeutic hypothermia, assessed using routinely collected National Neonatal Research Database data: a retrospective, UK population-based cohort study.The Lancet. Child & adolescent health · 2021Article
- Optimising nutrition during therapeutic hypothermia.Archives of disease in childhood. Fetal and neonatal edition · 2019Article
- Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate current nutritional practices during and after therapeutic hypothermia (TH) for infants with hypoxic-ischaemic encephalopathy (HIE) in UK neonatal units. STUDY
designEmail survey of neonatal clinicians.
settingUK neonatal units providing active TH. PATIENTS: Neonates cooled for HIE.
methodsEmail survey including questions regarding the timing of starting enteral feeds, volumes, frequency and parenteral nutrition (PN) use and availability of guidelines.
resultsForty-nine responses were received (49/69, 71%). The rate of enteral feeding during TH and rewarming was 59% (29/49). There was a significant linear trend for the increase in the proportion of units starting enteral feeds (p=0.001) during TH. As compared with post-TH period, significantly lower milk volumes were started during TH (median (range): 7.5 mL/kg/day (1.5-24) vs 17.5 mL/kg/day (7.5-30), p=0.0004). During TH, breast milk was primarily used by 52% of units predominantly as 2-3 hourly feeds, and volumes were increased as tolerated in 55% of units. Only 29% (14/49) of units used PN, with 86% (12/14) of those offering enteral feeds during PN. Guidelines for feeding during TH were available in 31% (15/49) of units.
conclusionsMany neonatal clinicians offer enteral feeds predominantly using expressed breast milk, with or without PN, during TH, although with huge variability. The heterogeneity in the nutritional practice underscores the need for assessing the safety of both enteral and parenteral feeding during TH.
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