Evidence map›Paper›PMID 29636876›Full record

ArticleAmerican journal of translational research2018

MiR-143-3p suppresses the progression of ovarian cancer.

Haijuan Shi, Huimin Shen, Juan Xu, Shanshan Zhao, Shuzhong Yao, Nan Jiang

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 82 citations in OpenAlex.

  1. Article
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  4. Hsa_circRNA_0101125 Promotes Proliferation, Migration, and Invasion of Esophageal Squamous Cell Carcinoma via miR-143-3p/ZNF148 Axis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  5. MicroRNA Is Downregulated in Invasive Non-Functioning Pituitary Adenomas.International journal of molecular sciences · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Haijuan ShiThe Second Affiliated Hospital of Guangxi Medical UniversityGuangxi, P. R. China.
Huimin ShenThe First Affiliated Hospital, Sun Yat-sen UniversityGuangzhou 510080, Guangdong, P. R. China.
Juan XuJinhua Municipal Central Hospital, Jinhua Hospital of Zhejiang UniversityJinhua 321000, Zhejiang, P. R. China.
Shanshan ZhaoThe First Affiliated Hospital, Sun Yat-sen UniversityGuangzhou 510080, Guangdong, P. R. China.
Shuzhong YaoThe First Affiliated Hospital, Sun Yat-sen UniversityGuangzhou 510080, Guangdong, P. R. China.
Nan JiangThe First Affiliated Hospital, Sun Yat-sen UniversityGuangzhou 510080, Guangdong, P. R. China.
Sun Yat-sen University · CNHenan Psychiatric Hospital · CNJinhua Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRNAs) are a class of naturally occurring, small, non-coding RNAs that target protein-coding mRNAs at the post-transcriptional level and participate in various biological processes. Our previous studies suggested that miR-143-3p functions as a tumor suppressor and has a role in the progression of ovarian cancer, in part through the regulation of the tumor promoter. In this study, we found that the mRNA expression level of miR-143-3p was significantly decreased in ovarian cancer tissues, in comparison with normal ovarian tissues by high-throughput miRNA profiling and quantitative RT-PCR. Secondly, we indicated that the up-regulation of miR-143-3p in the ovarian cancer cell lines SKOV3, ES2, and OVCAR3 significantly reduced their proliferation, migration, and invasion. Furthermore, miR-143-3p inhibited the growth of ovarian tumors

Indexed as

migrationMiR-143-3povarian cancerproliferationTAK1xenograft

Identifiers

PMID29636876
PMCPMC5883127
OpenAlexW2987848448

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.