Evidence map›Paper›PMID 29636869›Full record

ArticleAmerican journal of translational research2018

Ginsenoside Rb1 inhibit apoptosis in rat model of Alzheimer's disease induced by Aβ

Yiru Wang, Yan Li, Wenyu Yang, Shiyu Gao, Jianwei Lin, Tianqi Wang, Kailiang Zhou, Haiyan Hu

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Article
  3. Plants, Pills, and the Brain: Exploring Phytochemicals and Neurological Medicines.International journal of plant, animal and environmental sciences · 2025
    Article
  4. Article
  5. Ginsenoside RbChinese herbal medicines · 2024
    Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Journal of ginseng research · 2023
    Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yiru WangDepartment of Neurology, Wenzhou Traditional Chinese Medicine HospitalWenzhou 32500, China.
Yan LiDepartment of Traditional Chinese Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical UniversityWenzhou 325000, China.
Wenyu YangDepartment of Traditional Chinese Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical UniversityWenzhou 325000, China.
Shiyu GaoDepartment of Traditional Chinese Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical UniversityWenzhou 325000, China.
Jianwei LinDepartment of Traditional Chinese Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical UniversityWenzhou 325000, China.
Tianqi WangDepartment of Traditional Chinese Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical UniversityWenzhou 325000, China.
Kailiang ZhouThe Second Clinical College of Wenzhou Medical UniversityWenzhou 325003, China.
Haiyan HuDepartment of Traditional Chinese Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical UniversityWenzhou 325000, China.
Wenzhou Medical University · CNWenzhou Hospital of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is the most common form of dementia and lacks disease-altering treatments. Ginsenoside Rb1 (GsRb1), the key active compounds of ginsenoside found in ginseng. The present study aimed to determine whether GsRb1 could prevent cognitive deficit and take neuroprotective effects in Aβ

Indexed as

Alzheimer’s diseaseapoptosisB-cell lymphoma-2 (Bcl-2)Bcl-2 associated X protein (Bax)cysteinyl aspartate specific proteinase-3 (Caspase-3)Ginsenoside Rb1

Identifiers

PMID29636869
PMCPMC5883120
OpenAlexW2980511404

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.