Evidence map›Paper›PMID 29636801›Full record

ArticleEvolutionary applications2018

The effects of subcurative praziquantel treatment on life-history traits and trade-offs in drug-resistant

Mafalda Viana, Christina L Faust, Daniel T Haydon, Joanne P Webster, Poppy H L Lamberton

Abstract read
In one paragraph

Article in Evolutionary applications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Reconciling Egg- and Antigen-Based Estimates of Schistosoma mansoni Clearance and Reinfection: A Modeling Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Schistosomiasis: Life Cycle, Diagnosis, and Control.Current therapeutic research, clinical and experimental · 2019
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mafalda VianaInstitute for Biodiversity, Animal Health and Comparative Medicine University of Glasgow Glasgow UK.ORCID 0000-0001-5975-6505
Christina L FaustInstitute for Biodiversity, Animal Health and Comparative Medicine University of Glasgow Glasgow UK.ORCID 0000-0002-8824-7424
Daniel T HaydonInstitute for Biodiversity, Animal Health and Comparative Medicine University of Glasgow Glasgow UK.
Joanne P WebsterLondon Centre for Neglected Tropical Disease Research Department of Infectious Disease Epidemiology School of Public Health Imperial College London London UK.
Poppy H L LambertonInstitute for Biodiversity, Animal Health and Comparative Medicine University of Glasgow Glasgow UK.ORCID 0000-0003-1048-6318

Funding

Medical Research Council MR/N015320/1Medical Research Council MR/P025447/1Wellcome Trust
6 · The paper itself

Abstract

Natural selection acts on all organisms, including parasites, to maximize reproductive fitness. Drug resistance traits are often associated with life-history costs in the absence of treatment. Schistosomiasis control programmes rely on mass drug administration to reduce human morbidity and mortality. Although hotspots of reduced drug efficacy have been reported, resistance is not widespread. Using Bayesian state-space models (SSMs) fitted to data from an

Indexed as

drug resistanceestablishmentfecundityfitness costspraziquantelreproductionSchistosomastate‐space modelssurvival

Identifiers

PMID29636801
PMCPMC5891057

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.